# Insulin Doctor: This Is The First Sign Of Dementia! The Shocking Link Between Keto & Brain Decline!

https://www.youtube.com/watch?v=KVXnVe8eOkM

[00:00] Welcome to the sardine challenge. So,
[00:01] the only thing on the menu for the next
[00:03] 3 days is sardines. I challenge you to
[00:05] try and eat three of those cans in a day
[00:07] because that's a hell of a tool to help
[00:09] you get into a ketogenic state. And when
[00:11] you're in a ketogenic state, it helps
[00:13] burn fat, muscle mass gets higher
[00:15] preserved. I've seen patients that have
[00:16] reversed their gray hair and their brain
[00:18] performance, concentration, and energy,
[00:20] all of those things improve. And so, I'm
[00:22] going to teach you how to do an advanced
[00:23] ketogenic diet.
[00:25] Sorry, the sardine juice has gone on my
[00:27] iPad.
[00:27] >> Good luck getting that off. Dr. Annette
[00:30] Bosworth is the insulin resistance
[00:31] specialist.
[00:32] >> With over two decades of experience,
[00:34] she's discovered that the key to your
[00:35] health isn't more treatments.
[00:37] >> It's to get into a ketogenic state. Most
[00:40] people have been making buckets of
[00:41] insulin without knowing it. But when you
[00:42] have excess insulin, it's a chronic
[00:44] disease maker. It is what makes high
[00:46] blood pressure. It is what makes cancer.
[00:48] It is what makes debris in the brain,
[00:50] which is linked to depression, brain
[00:52] fog, Alzheimer's, and Parkinson's. And
[00:54] so, to reverse the high insulin state, I
[00:56] really push my patients to do the
[00:58] ketogenic diet. And what I'm told is
[01:00] your best life ahead within a year.
[01:02] Like, I really rescued my mom from the
[01:04] edge of death. So, where do I start?
[01:07] >> First thing is quit eating so late at
[01:08] night because you're stimulating an
[01:10] excessive production of insulin. The
[01:11] next thing, keep the carbs low, put the
[01:13] fat up, more eggs, beef brisket, ribs,
[01:16] pork belly.
[01:16] >> But then people often say when you talk
[01:18] about the ketogenic diet that it's not
[01:19] sustainable. So, you have this idea of
[01:21] this keto continuum, consistently keto
[01:24] for life.
[01:24] >> Yeah. I mean, I've been on a ketogenic
[01:26] diet for 10 years. And those 12 steps
[01:28] are it. And you're not going to have to
[01:29] try very hard. So, the first step is
[01:32] I see messages all the time in the
[01:34] comment section that some of you didn't
[01:35] realize you didn't subscribe. So, if you
[01:37] could do me a favor and double-check if
[01:39] you're a subscriber to this channel,
[01:40] that would be tremendously appreciated.
[01:42] It's a simple, it's a free thing that
[01:44] anybody that watches this show
[01:45] frequently can do to help us here to
[01:47] keep everything going in this show in
[01:48] the trajectory it's on. So, please do
[01:50] double-check if you subscribed. And
[01:52] thank you so much because in a strange
[01:53] way, you are you're part of our history.
[01:56] And you're on this journey with us and I
[01:57] appreciate you for that. So, yeah, thank
[01:59] you.
[02:03] Dr. Annette Bosworth or shall I call you
[02:06] Dr. Boz?
[02:08] What is it that you
[02:09] know and believe and understand that you
[02:11] think the general public doesn't know,
[02:13] believe and understand?
[02:15] Mhm.
[02:16] So, most of the reasons people come to
[02:18] see me
[02:19] could be reversed if they knew how to
[02:21] make ketones on a regular basis.
[02:24] So, I'm an internist.
[02:25] Uh that means uh if you go to an
[02:27] internal medicine doctor and we don't
[02:29] know what's wrong, you're going to die.
[02:32] We take care of tough puzzles and we do
[02:34] this over a long management, chronic
[02:36] disease management. So, I've got 25
[02:39] years of studying chronic problems that
[02:42] deteriorate the quality of life.
[02:45] Lifespan, healthspan both go in the
[02:47] toilet when you're chronically seeing
[02:48] me.
[02:49] And you could abort all of that destiny
[02:53] if routinely you were making ketones.
[02:56] An internist sounds like an intern. I'm
[02:58] trying to understand the the definition.
[03:00] >> on this is terrible. It just means
[03:02] you're supposed to take care of very
[03:03] complex answers. Your job I mean, the
[03:05] buck stops with you. If if the internal
[03:07] medicine team can't figure it out,
[03:09] you're going to die. So, so you're
[03:10] basically a chronic illness doctor.
[03:12] >> Chronic disease management is absolutely
[03:14] it. You know, I love the way uh Peter
[03:16] Attia uses medicine 2.0, which is what
[03:19] we are the masters of, managing it,
[03:21] making sure the prescriptions are there,
[03:23] making sure you are treating all these
[03:24] problems.
[03:26] The internist being one of your best
[03:27] buddies cuz you're having to see them
[03:29] routinely, you got to get the meds
[03:30] refilled, you got to check for the side
[03:32] effects. It's a mill. What is medicine
[03:34] 2.0 in your definition? Yeah, so I can
[03:37] keep you from dying from childbirth and
[03:39] infections and I have an antidote for
[03:41] every one of your symptoms. We are in a
[03:44] world where medicine has answered a lot
[03:45] of problems. Little things like high
[03:47] blood pressure, little things like it's
[03:49] a few extra pounds around the middle,
[03:50] little things like brain fog, oh, my
[03:53] eyes are aging. All of these are signals
[03:56] that your body has made more trash than
[03:59] it cleaned up and there were some rules
[04:01] to humans that you missed.
[04:04] And for for my listeners that have
[04:05] clicked on this conversation,
[04:08] what are they going to get out of giving
[04:09] us their time and staying with us and
[04:12] listening to this? What is the end goal
[04:13] going to be for them in their lives?
[04:15] Listening to the way I talk to my
[04:17] patients and teach them the steps how to
[04:20] reverse the medical problems that you've
[04:22] already got on the roster.
[04:24] And by doing that, the freedom
[04:27] is to be the kind of grandparent that
[04:29] you dreamt of, but you've surrendered
[04:31] can't be there anymore.
[04:33] And what is the list of predicaments or
[04:35] illnesses that Yeah. So
[04:37] >> are relevant here? Most common one is
[04:38] being overweight and a brain that's not
[04:40] working right. What really is behind all
[04:43] of the patients I've seen for 25 years
[04:44] is
[04:45] we're working on peak brain performance.
[04:47] Even if you don't think about that,
[04:48] that's what I think about. So when you
[04:50] come in and you're 55 years old and I
[04:53] can see the worry of Parkinson's headed
[04:55] your way. Super young is 55 years old
[04:57] with Parkinson's. That is a brain that's
[04:59] got too much trash and you don't know it
[05:02] yet.
[05:03] And I mean, in the history of Dr. Boz
[05:06] versus Parkinson's,
[05:08] Parkinson's has like 3,500 patients, I
[05:10] have zero. Parkinson's wins every time.
[05:13] And the the biggest moment of people who
[05:15] have chronic problems under the hood
[05:18] is they have no idea that it's coming.
[05:21] And once that lands, the reversal is
[05:23] much worse. Seeing it 10 years before
[05:25] it's supposed to be there,
[05:27] this is a gift of saying, let me show
[05:28] you how to undo that. Back away from the
[05:30] edge. It's that brain function that
[05:32] you're going to miss the most when it
[05:34] doesn't work.
[05:36] And it's linked to all of these things
[05:37] like the arthritis, the you know, weight
[05:40] around the middle, the high blood
[05:41] pressure, the
[05:43] severe connection to mental
[05:46] uh
[05:46] approach, meaning you can say
[05:48] depression, but people say, "Oh, I don't
[05:49] have that diagnosis." I'm talking about
[05:51] a brain that doesn't want to engage,
[05:53] that doesn't find joy in their life
[05:54] anymore, because it's been too many
[05:57] years since they took out the trash. Let
[05:59] me show you how to take out the trash,
[06:00] and you're going to have to do it a few
[06:01] times,
[06:02] but what unfolds is your best life ahead
[06:05] within a year. So, you're going to teach
[06:07] me how to take out the trash? Yeah. The
[06:09] trash in my own brain. Yep.
[06:11] And if I take out the trash in my own
[06:12] brain, how is my life going to be
[06:13] better?
[06:14] You live in the 21st century, where
[06:16] there's lots of processed foods and lots
[06:17] of ways that your body did things
[06:19] without telling you.
[06:20] So, any injury that you've had, like a
[06:22] joint injury that keeps coming back
[06:23] every time you injure it, it is a little
[06:25] easier to injure the next time.
[06:27] Is there a ring around the middle that's
[06:30] more more than pinch an inch?
[06:33] Is there a uh,
[06:35] distance in time where you say, "I can
[06:38] focus for this many hours, but I can't
[06:39] do it for this many hours anymore"?
[06:41] Those are all places where if you did
[06:44] this, if you were able to say, "Don't
[06:46] stop taking out the trash several times
[06:48] a year, several times a month if you ask
[06:50] me." Then you never have to come into
[06:52] this world that
[06:54] I just see people they're they're in
[06:55] quicksand, they're up to their waist.
[06:58] And getting them out, they need a real
[06:59] lifeline.
[07:01] And what are the current solutions
[07:02] people are typically offered when
[07:03] they're feeling, you know, all the
[07:05] the ways that you described there, where
[07:07] they just don't feel good, they have
[07:08] brain fog, they're they might have
[07:10] chronic pain setting in in various ways.
[07:11] What are the typical solutions that
[07:13] medicine 2.0 would offer them? Yeah,
[07:15] especially if they have good insurance.
[07:17] Yeah. That doctor is going to be with
[07:18] the covered insurance plan, and he's
[07:21] going to say, "Tell me the symptoms.
[07:23] I have a matching game. I will give you
[07:25] the drugs that will take away that one,
[07:27] and take away that one, and take away
[07:28] that one."
[07:29] What is always a downside is, well, play
[07:33] that forward for 10 years. Play it
[07:34] forward 5 years.
[07:36] And are the symptoms gone? No, but it
[07:38] will bridge and hold up the architecture
[07:40] of the body and the human without
[07:42] actually fixing the problem without
[07:44] actually diving in and say you got some
[07:46] chemistry problems under the hood that
[07:48] you don't measure and you don't talk
[07:50] about. But if you did even if you're not
[07:52] perfect, even if you're 70%
[07:55] you're going to find yourself
[07:57] at the age of 54 with vitality and
[08:00] energy and sleeping through the night
[08:02] and not having what every other
[08:03] 54-year-old which is chronic joint pain,
[08:06] a brain that can only focus for 3 to 4
[08:08] hours without a break,
[08:09] a a stamina of endurance and health and
[08:13] and joy that falls apart. So when I'm
[08:17] you're 54 years old, when I'm 54 years
[08:18] old, I want to be as
[08:21] young and energetic and articulate
[08:24] and cognitively astute as you are.
[08:27] So what should I be doing now to make
[08:29] sure that I don't decline, decay in all
[08:32] those areas I described? Oh, what did
[08:34] you have for breakfast? Today? Yeah.
[08:36] Um I have not eaten breakfast yet. Okay,
[08:40] that's not a bad thing, but when you're
[08:42] 54, you should probably put the calories
[08:44] in the morning, not at night. We know
[08:46] that as you age, the cost of a calorie
[08:50] turns into timing.
[08:52] If you eat that food one bite of food
[08:54] after 6:00
[08:56] is worth 10 bites of food before noon.
[08:59] So if you're trying to say how do I get
[09:01] the best out of the nourishment, but
[09:03] also eating's fun, if you only get one
[09:05] bite after 6:00 and 10 before
[09:08] move that food towards morning.
[09:11] When you're your age, what did you have
[09:13] for what's the last meal you ate?
[09:15] Yesterday? Yeah. Uh for dinner I had
[09:18] this cod and I had salad.
[09:21] I also had pasta.
[09:23] Okay.
[09:24] But I ate pretty late, which is about
[09:25] 9:00. What did you have the rest of the
[09:26] day before that? Was that your first
[09:28] meal?
[09:28] >> Just a big salad. Was that more towards
[09:31] lunch or noon or
[09:33] Probably about 4:00. So waited all the
[09:35] way till 4:00 to eat. Very common. This
[09:37] is a really common pattern of people
[09:38] doing what we would say intermittent or
[09:40] time restricted eating. They put that
[09:42] eating window in this, but it's got that
[09:44] balloon at the end of the day. Yeah. And
[09:46] it really does I mean what you're
[09:48] stimulating is an excessive production
[09:50] of insulin.
[09:52] And you're going to wake up the next
[09:53] morning. What time did you wake up this
[09:54] morning?
[09:55] Today? I went to bed fairly relatively
[09:58] early for me. I woke up at about 7:30
[10:00] a.m. Oh. Usually it's later. And do you
[10:02] have Did you have a solid 7 8 hours of
[10:05] sleep or how? Yeah. So during that time
[10:09] uh you finished eating around 10:00 then
[10:10] it sounds like. Yeah. Okay. So then it's
[10:12] 7:30
[10:13] >> Maybe a little later. Okay. So 11:00 and
[10:15] you've got uh
[10:16] 7:30 in the morning is when you woke up.
[10:18] So that's about 8 hours since you've
[10:19] eaten. Your insulin is still churning.
[10:22] Especially if the meal was large and
[10:24] there was carbs in it. So now you've got
[10:25] these processed foods late at night and
[10:28] you're at the beginning of the disease,
[10:29] right? You're at the beginning of the
[10:31] chronic inflammatory churn of how do you
[10:34] age faster and faster? You don't do
[10:36] that. You don't have high insulin
[10:37] throughout the night. So can you explain
[10:39] to me like I'm a 12-year-old what
[10:42] insulin is and the role it's playing cuz
[10:44] you know I guess we're focused here on
[10:46] how to
[10:47] I guess longevity aging for a second,
[10:49] but how does insulin play a role in all
[10:51] of this and what is insulin? So insulin
[10:54] insulates.
[10:55] Okay? So think of it as it makes you
[10:57] fluffy. It makes you It puts the fat on.
[10:59] Uh
[11:00] it's got some other roles, too. But
[11:02] we're going to talk about chronic
[11:03] diseases here where it's not a scarcity
[11:05] problem. You You make plenty of it. And
[11:08] when it's in excess, it will store
[11:12] energy for when you go through a famine.
[11:14] It will also cause you to grow.
[11:17] Now grow means get a little fatter, but
[11:20] it also means things like their skin
[11:22] gets a little thicker, they have skin
[11:24] tags, and what I always think about is
[11:27] what's going on in their brain. And when
[11:29] that insulin is high for years and years
[11:31] and years
[11:32] uh just like yours, because if if you
[11:34] didn't eat the rest of today
[11:36] and then you got up tomorrow morning, it
[11:38] would be about that long after a late
[11:40] meal last night, that's how long it
[11:43] would take you to say,
[11:44] "Okay, we're back down to where we
[11:47] started from or where we should be in
[11:48] the morning." For someone that's never
[11:49] had the insulin before, there's some
[11:51] context to give on in terms of what it's
[11:52] doing. So, it's coming out like a
[11:54] transporter and helping put away the
[11:56] sugar or deal with the excess sugar.
[11:58] Right. So, it is what what Yeah, it
[12:00] lifts glucose or sugar from the
[12:02] circulation into a cell. That's its
[12:04] first primary job.
[12:06] But if all the cells are full, their
[12:08] storage is full, it's going to start to
[12:10] pack it into the liver. And then let's
[12:11] say all those stores are full, too. This
[12:14] job of the of insulin, this hormone
[12:17] oozes into every part of your body to
[12:20] say, "Make sure it's got full fuel. Make
[12:21] sure it's got that sugar."
[12:23] But most people are like what I would
[12:26] guess you are. Most of the time you
[12:28] don't you aren't in a shortage of sugar.
[12:30] And so, it fill it tops things off
[12:32] and then it will turn things into fat.
[12:34] It's too much sugar, they can't store
[12:36] it, all the storage is full. So, you can
[12:37] send the signal out, "Make me some more
[12:39] cells. I need some more storage units.
[12:41] This guy is eating more than he thinks
[12:42] he is. And we're going to be prepared to
[12:45] live through the famine."
[12:48] But in the meantime, turn it into fat.
[12:51] Make him a little fluffier. Is that the
[12:53] only consequence of high insulin is that
[12:55] I'm going to I might be a bit more fat?
[12:57] No, that's just the one people hear
[12:58] about the most. When you look at chronic
[13:00] disease management, it is the growth
[13:03] of of the diseases, of the inflammation.
[13:06] It's the making of the trash.
[13:08] So, I just keep saying, you know, you
[13:09] need to take the trash out routinely,
[13:11] which means that insulin, which has been
[13:13] smoldering higher than you think it is,
[13:16] because you live in today's world,
[13:17] because you eat processed food, because
[13:18] you eat super late at night, uh you
[13:20] don't go two to three days without
[13:21] eating. You've You've got storage filled
[13:23] in your body.
[13:25] The high insulin levels in a healthy
[13:27] person
[13:28] hides
[13:30] that the debris is being made and you
[13:31] don't know it.
[13:32] Yeah, it hides it. Yeah, it's going to
[13:34] put it in between two cells in your
[13:36] brain. It's going to put it in between
[13:38] the skin cells. The trash doesn't get
[13:40] taken out until the insulin gets lower.
[13:43] And unfortunately, most people
[13:47] have been making buckets of insulin
[13:48] without knowing it.
[13:49] Why?
[13:51] What are they doing to create buckets of
[13:52] insulin? All the things you said about
[13:54] >> Carbs.
[13:55] Um
[13:55] foods that comes from boxes and barcodes
[13:58] and
[13:59] bags instead of whole foods, instead of
[14:03] a fat forward diet which would then push
[14:06] that body into
[14:08] making ketones. So, you can't you cannot
[14:11] make a ketone
[14:12] if your insulin's high.
[14:14] Are there any signs that I might have
[14:17] high levels of insulin or insulin
[14:18] resistance? Abdominal girth is the first
[14:20] thing that is the first place that the
[14:22] fat goes. And so, you do this really
[14:24] great part where you don't eat until
[14:25] later in the day. Mhm. How does that
[14:27] feel during the day?
[14:29] During the day I feel really focused. I
[14:31] actually don't even know that I'm not
[14:31] eating. So, that's really good. So, what
[14:33] I would love to know is show me what
[14:35] your blood sugars are doing during the
[14:36] day and show me if you make ketones.
[14:38] That'll be The answer is you when you
[14:41] have excess insulin, which is this
[14:44] chronic disease maker,
[14:46] it is what makes cancer. It is what
[14:48] makes high blood pressure. It is what
[14:50] makes debris in the brain where call it
[14:52] depression or brain fog or Parkinson's.
[14:55] It's the aging of the brain. It's linked
[14:57] to all of those things.
[14:58] >> All of those things. And that excess
[15:00] insulin nobody tells you about. But, the
[15:02] symptoms are dang, I feel like I got to
[15:05] eat every two to three hours. Uh their
[15:07] debris or their fuel keeps running out.
[15:10] When you say, "Boy, I can eat
[15:12] once at the end of the day and I'm
[15:14] pretty good. My focus stays really
[15:16] good." What I want you to prove is what
[15:18] are your ketones during the day? So,
[15:20] when when you've got a patient who has
[15:22] done that,
[15:24] their ketones will be 0.7,
[15:26] 1.0,
[15:28] and they're taking out the trash all day
[15:30] long.
[15:31] So, there's these two energy sources.
[15:32] One of them is the glucose. One of them
[15:34] is which is from like, you know, eating
[15:35] pasta, which I ate last night. Um so,
[15:38] that probably put a lot of glucose in my
[15:39] my blood. I probably had a high glucose
[15:41] spike, and then insulin came out to deal
[15:42] with that. And then there's ketones,
[15:44] which start to appear when I'm fasting
[15:47] or when I haven't been eating carbs for
[15:49] a while and my body's looking for an
[15:50] energy source.
[15:51] >> Yeah, when In terms of these two energy
[15:54] sources,
[15:56] there seems to be a lot of hype around
[15:57] ketones.
[15:58] >> Mhm. So, why doesn't our body just run
[16:01] off ketones? It will, as soon as you're
[16:03] done lowering your insulin. And I mean,
[16:06] insulin grew in these patients. They
[16:08] didn't know that it was growing high.
[16:10] They went to their blood test, and their
[16:11] glucose looked normal. What nobody
[16:14] checked for years is how much of that
[16:15] insulating hormone did it take to keep
[16:18] the glucose controlled. And that's where
[16:20] chronic diseases are are grown in
[16:22] spades. That's where autoimmune disor-
[16:23] >> The insulating hormone being insulin.
[16:25] Yes.
[16:25] >> Okay. So, that excess insulin for the
[16:27] last decade,
[16:29] had you come into my clinic, we'll put a
[16:31] label on it, call it PCOS, call it high
[16:34] blood pressure, call it
[16:36] autoimmune problems. All of them are
[16:39] linked to high insulin. Glucose, when
[16:41] you want to store it, we put it in a
[16:43] fancy string called glycogen. And it's
[16:45] just an efficient way to store glucose,
[16:47] but as soon as your body needs it, it
[16:49] will unlock all that sugar back into
[16:51] your access back for you.
[16:52] >> Mhm. What you don't realize is, well,
[16:55] how much glycogen you got stored over
[16:57] there?
[16:58] How much is there in storage? And that
[17:00] is what high insulin has been doing.
[17:02] Just put it in storage, put it in
[17:03] storage. And then, when you stop eating,
[17:07] you'll know if you emptied out all your
[17:09] stored sugar, which is some of the
[17:11] regular sugar you just ate, but then all
[17:13] this glycogen, this packaged sugar.
[17:15] How empty are you? I don't know. Have
[17:18] you made a ketone yet?
[17:20] You cannot make a ketone. You cannot
[17:21] burn fat until that that tank is empty.
[17:24] Okay, so I have these glycogen stores
[17:26] which last for well, a day or two. Oh,
[17:28] no. Think of it as brown sugar.
[17:31] So, you package the sugar really tight.
[17:33] Then you put it in the back of the
[17:34] drawer and it turns crusty cuz you never
[17:36] lowered your insulin. I have patients
[17:38] that are over overweight and we put them
[17:40] on a ketogenic we put them on a 20 total
[17:43] carbohydrates per day. So, super low
[17:44] carbohydrate.
[17:46] It is 15 days before they make a ketone.
[17:49] Okay, so it's it could be a a while it
[17:51] could be up to 2 weeks for example
[17:53] before my glycogen stores are empty. And
[17:55] it's not until my glycogen stores, my
[17:56] glucose stores are empty that my body
[17:58] can start producing ketones. Correct.
[18:00] So, it's going to exhaust all of those
[18:01] glycogen stores and then once it's run
[18:04] out, it's going to switch into this
[18:05] ketogenic state. Right.
[18:07] Yeah, so think of it as your short-term,
[18:10] easy to access sugar has to decrease.
[18:13] And that means your insulin has
[18:15] decreased.
[18:16] That hormone for insulin, they both run
[18:18] in tangents. You decrease your emptying
[18:20] glycogen, your insulin's going down. So,
[18:22] how do I know if I have insulin
[18:25] resistance? What are what are the key
[18:27] signs? You mentioned skin tags. I've
[18:28] never heard that term before. Yeah, skin
[18:30] tags are not moles. So, moles you can
[18:33] feel this bump on your on your skin,
[18:34] right? But a skin tag has a neck and
[18:37] like a little mushroom.
[18:39] And it's the most annoying thing when
[18:41] patients come and say, "Well, I just
[18:42] tried to cut them all off, but they kept
[18:44] bleeding."
[18:45] I'm like, "Do not cut them off."
[18:47] They'll fall off
[18:49] when your insulin's lower. So, that's
[18:50] the first place. It'll be found in their
[18:52] armpits or places where the skin rubs.
[18:53] So, armpits and their groin. And once
[18:56] insulin starts to grow them, it's like a
[18:57] crop. A crop a little baby cauliflower
[19:00] hanging out in their armpits. You talked
[19:02] about velvety skin
[19:03] >> Yes. as well being an an indicator.
[19:05] Velvety skin is this Latin word
[19:07] acanthosis nigricans, which is fancy
[19:10] word that means the skin is darker and
[19:13] thicker. So, the the places that usually
[19:15] happens is the back of the neck. And
[19:17] you'll hear, you know, stories of I
[19:19] tried to wash my neck. It's It's dirty
[19:21] all the time. It's not dirt. It is the
[19:24] way the skin is under the the curse of
[19:28] high insulin. And you see it in
[19:29] teenagers all the time now. They put on
[19:31] weight and their growth hormones are
[19:33] already doing that teenage thing. Now,
[19:36] you put high insulin in there and they
[19:38] have this dirty neck syndrome. Or on the
[19:40] creases of their elbow. It's just darker
[19:42] here.
[19:43] Uh that is pathology. That's not normal
[19:47] from high insulin. You talked about
[19:49] weight changes as well. What What's this
[19:50] thing about hairy toes that I was
[19:52] reading about?
[19:52] >> Right. So, as my patients age, so most
[19:55] my 55-year-olds that have had high
[19:57] insulin, I will tell them, look at your
[19:59] toes. They're supposed to have hair on
[20:01] them.
[20:02] And when your body has had that high
[20:05] insulin state for a couple decades now,
[20:07] it will start to say, we don't send
[20:10] resources to a couple parts of the body
[20:12] anymore.
[20:13] And the follicles in their toe
[20:15] are one of them. Like, you just stop
[20:16] growing hair on your toes. And there's
[20:18] an ascending problem with this where the
[20:20] toe starts, then it's the ankles, then
[20:22] it's up to the knees, and they don't
[20:23] have hair anywhere on their lower
[20:24] extremities.
[20:25] It is a process
[20:28] that started from high insulin. What
[20:29] about aging? You talked about how if you
[20:32] have high insulin, there'll be an impact
[20:34] on your aging. Now, I'm thinking about,
[20:36] you know, I'm getting a couple gray
[20:37] hairs now. I'm thinking this is because
[20:39] of my insulin levels. I I have seen
[20:41] patients that have reversed their gray
[20:43] hair on a ketogenic diet. It blew my
[20:45] mind. They asked me for the reason why
[20:46] that happened and I thought,
[20:48] well, um the cells are healthier that
[20:51] are making your hair. That's all I got.
[20:53] Um aging is exactly that enemy, which is
[20:58] they are going around the sun with more
[21:00] growing of the trash than they needed.
[21:04] So, that high insulin, they don't know
[21:05] about it. They've not produced a ketone
[21:07] in years, and that chronic disease is
[21:10] now
[21:11] difficult to get their the eye to clean
[21:14] out. It's difficult to get that brain
[21:17] trash removed. And you're supposed to do
[21:19] it every night when you sleep. It's not
[21:20] supposed to be behind this far. You're
[21:22] two decades from taking out the trash in
[21:24] your brain. That's aging. How do I first
[21:28] start even know my ketone blood levels?
[21:31] Well, when when a patient first comes in
[21:33] saying, "How do I begin?"
[21:35] I want them to tell me what they had for
[21:37] their meal and then say, "How many carbs
[21:38] do you think that was?"
[21:40] Because this education like an apple is
[21:42] 20 g of carbs, 15 g of carbs for some of
[21:45] them.
[21:46] And we're going to ask you in the first
[21:49] 6 weeks to take your carb intake down to
[21:51] less than 20. 20 total g of
[21:54] carbohydrates or less is where we begin.
[21:56] And again, I do this in a medical grade.
[21:58] There are people who play with the
[21:59] ketogenic diet, and there are people who
[22:01] try to reverse medical problems with a
[22:02] ketogenic diet. In order to do this, it
[22:05] is not a lazy kind of keto. You have to
[22:07] actually be on the same team as me using
[22:09] data to reverse this medical problem.
[22:12] And how how does one measure the blood
[22:15] ketone levels? Yeah, I I think blood is
[22:17] the best. There is a way you can measure
[22:19] them in a in urine. The burning of fat,
[22:22] if you
[22:24] turn that string of fat into ketones,
[22:26] there are two destinies for that. You
[22:28] either put it into a mitochondria and
[22:30] turn it into energy or you pee it out.
[22:32] So, especially when they're early in a
[22:34] ketogenic journey, they're they
[22:36] overshoot. Evolution said, "Don't let
[22:39] them die.
[22:40] Turn that fat into energy. Help them
[22:42] through the famine." So, the excess
[22:44] ketones they make end up in their urine.
[22:47] We call them pee tone strips, and
[22:49] they're cheap and easy, and we don't
[22:50] have to cross that barrier of somebody
[22:52] pricking their finger at the beginning.
[22:54] So, they're going to pee out ketones
[22:56] every day
[22:58] as long as they're not chronic insulin
[23:01] resistant. So, if I avoid carbs for a
[23:04] sustained period of time, which could be
[23:06] a couple of days, it could be up to 2
[23:07] weeks, eventually my body's going to
[23:09] say, "Listen, we need energy." So,
[23:11] it's going to start burning my fat
[23:12] stores.
[23:13] >> Yes. You know, from some of that fat
[23:15] around the midsection, and it's going to
[23:17] start turning that into ketones, which
[23:19] are a
[23:20] different type of energy. Are there any
[23:23] reasons why ketone as a source of energy
[23:26] is better for me in terms of performance
[23:29] other than the insulin reasons that
[23:31] we've talked about? Like, are there any
[23:33] other parts of my body or my health that
[23:34] benefit from ketones?
[23:36] >> For starters, when you're burning a
[23:37] ketone, there's less trash. Okay? It is
[23:40] a cleaner
[23:41] fuel with less byproduct, especially as
[23:44] you age. So, you get the longer energy,
[23:46] and you have less debris floating
[23:47] around. You hear the word antioxidants
[23:50] all the time. Well, burning ketones is
[23:53] an antioxidant state. It is a and it's
[23:55] in the space where you need it, which is
[23:57] inside that cell. Uh you swallow
[24:00] antioxidants, and you have no guarantee
[24:02] that they end up where they're supposed
[24:03] to.
[24:04] So, number one, the fuel is reducing
[24:07] trash at a cellular level, it lasts
[24:10] longer, and it penetrates through that
[24:13] blood-brain barrier to fuel a brain that
[24:17] even if it's insulin resistant, it can
[24:19] use a ketone.
[24:20] So, the problem with somebody who's
[24:22] chronic insulin resistance, their brain
[24:25] needs a lot of glucose to stay on
[24:28] online.
[24:29] And I can try to get it there, but
[24:31] insulin is constantly fighting that.
[24:33] It's a war to try and keep the glucose
[24:35] in their brain.
[24:36] My hack is ketones will go right around
[24:40] that. It doesn't need the same
[24:41] transporters to get across the
[24:42] blood-brain barrier, and especially to
[24:44] fuel those cells in the brain. So, for
[24:46] performance,
[24:48] um I mean, name a game where you don't
[24:50] use your brain.
[24:51] There isn't one, right? You're You're
[24:53] going to If you're looking at
[24:54] performance to say, "Let's begin with
[24:56] the sharpest brains and the most
[24:57] focused, the most disciplined, the less
[25:00] um impulsivity.
[25:02] All of those things improve when that
[25:04] brain is being fueled with ketones.
[25:06] So, let's focus on the brain part then.
[25:07] So, what have you personally noticed as
[25:10] someone who I assume is in the ketogenic
[25:12] diet right now? Yes. What have you
[25:14] noticed the variances between when
[25:16] you're in a keto diet and when you're
[25:17] not? Right. Well, I've been doing this
[25:19] since 2015. So, um the onset of it was
[25:22] really messy, but uh the seasons where I
[25:25] would do a great job and then I would
[25:28] think, "Ah, I'm fine."
[25:30] Uh
[25:30] I I mean, I can tell you you see 25
[25:32] patients in a day and I feel bad for the
[25:35] last five.
[25:36] Uh they've got a they've got a sluggish
[25:38] brain. I don't care how much coffee
[25:39] you've got in you, you can't keep that
[25:41] focus for that length of time. Um when
[25:44] you're in a ketogenic state and not in a
[25:46] ketogenic state, uh the the the
[25:48] brainpower, the concentration, the
[25:50] ability to keep your mood controlled is
[25:53] is just
[25:55] it is a night and day difference for
[25:56] most people, but uh I think especially
[25:58] for me like
[25:59] uh I'm pretty high energy and when it
[26:01] runs out, I get crabby.
[26:03] Uh and that's not a good place to be if
[26:05] you're the patient.
[26:06] Yeah, I think I've noticed that as a
[26:07] podcaster, but I've also had a lot of
[26:09] very well-known podcasters say the same
[26:11] thing, which is the variance in their
[26:13] ability to speak and articulate
[26:14] themselves and think and sit here for 3
[26:16] to 4 hours having a conversation is
[26:18] night and day when they are in a fasted
[26:20] ketogenic state versus or on a ketogenic
[26:23] diet versus when they are in a higher
[26:26] carb diet. Right. And it's so profound
[26:28] to me that I that I almost wonder why
[26:30] like more people don't Oh, it's it's
[26:32] insane. Like one of the best things that
[26:34] I've done in 25 years was I went out on
[26:36] a limb and said, "I'm going to try and
[26:38] teach 200 people at once how to do this
[26:40] intense ketogenic diet for 3 weeks."
[26:44] Uh it is hardcore. This is not playtime.
[26:46] You're checking your numbers every day
[26:48] and you're comparing them to your
[26:49] classmates.
[26:50] And what you get to see in this class of
[26:52] 200 people going with an extreme
[26:54] ketogenic diet
[26:56] is the testimony you just said. I cannot
[26:59] believe how good I feel. By the end of 3
[27:00] weeks, they're naming babies after me.
[27:03] They They think this is a miracle. And
[27:06] I'm like, exactly.
[27:08] I mean
[27:09] when you do it in a group like that,
[27:11] I don't need to advertise. They tell
[27:12] their friends. They tell their Like if
[27:14] you want to be on a ketogenic diet that
[27:16] really wakes up your brain. I didn't
[27:18] think I could do this. I thought I was
[27:19] too old for this level of energy.
[27:22] And it's there within 3 weeks of doing
[27:24] it right. How long does it typically
[27:26] take on average for someone to feel
[27:28] those brain benefits from doing the
[27:30] ketogenic diet?
[27:32] Typically, how long does it take you?
[27:34] Me? Yeah. I rarely go out of it. Meaning
[27:36] I I might have a couple of days where I
[27:39] fly to LA and have a fancy meal and then
[27:40] I need to be back on it. It just doesn't
[27:42] feel good anymore.
[27:43] So, but let's go let's go to when I was
[27:45] overweight, okay? So, you say who's
[27:47] insulin resistant? Any person who's had
[27:50] a baby. Okay? You have to be insulin
[27:52] resistant to hold that baby for 9
[27:53] months. Okay? So, I had three of them
[27:56] and then the weight never came off on
[27:57] that third one.
[27:58] So, here is an insulin resistant person
[28:00] at 40-something years old
[28:02] and I am probably 60 lb heavier than I
[28:05] am now.
[28:07] And the first time it it
[28:09] I tried to get into a state of ketosis
[28:11] for like 9 months. I was about to give
[28:14] up on Like why can I not be a ketone?
[28:17] Why does every I mean I'm a doctor. I'm
[28:19] trying to use this for my brain
[28:20] patients, but I'm afraid to tell them
[28:22] about it cuz I personally cannot keep be
[28:25] a ketone. I mean I was trying to follow
[28:27] 50 carbs, then I tried to do 30 carbs,
[28:29] and then I tried to do none, but
[28:31] I just couldn't make it long enough into
[28:33] that ketogenic state. And what had
[28:35] happened is at least a decade of high
[28:37] insulin. Three babies, full practice,
[28:39] busy life, you know, on call, those
[28:42] kinds of things that are all dangerous
[28:43] if you're going to try to have a peak
[28:44] brain.
[28:46] I took my kids on a
[28:49] 22-mile hike around the city
[28:52] on Memorial Day in the name of troops'
[28:55] mental health. And I said, "If I am not
[28:57] peeing a ketone after walking 22 miles,
[29:01] having fasted for a day, then I'm for
[29:03] sure that this diet is a phooey."
[29:05] So, that's how much energy it took for
[29:07] me to pee a ketone.
[29:09] Because I was very insulin resistant. I
[29:10] had been making excess insulin for a
[29:12] decade, and I'm a doctor. I I should
[29:14] have known that.
[29:15] My sugars are fine.
[29:17] My hemoglobin A1C wasn't bad.
[29:19] But that excess insulin, that stored
[29:21] sugar, that stored glycogen, it took
[29:24] forever to get that low.
[29:26] And only after I fasted and then walked
[29:29] 22 miles did I pee a ketone.
[29:32] So, I When you ask the question, "How
[29:33] long does it take?"
[29:35] I don't make a I do a much better job
[29:36] now of telling people how to get there
[29:38] cuz I I almost gave up thinking, "This
[29:40] is junk science." If you if you were to
[29:42] eat a high-carb meal now and take a
[29:45] couple of days off, how long would it
[29:46] take you to get back into a ketogenic
[29:48] state where you have those brain
[29:49] benefits now? Uh I could probably flip
[29:51] back in within 12 hours.
[29:53] So, that's how long it roughly takes for
[29:55] someone who's got a bit in better
[29:57] metabolic shape, it will take a couple
[29:59] of days. Mhm. Um
[30:02] is there a downside to living in ketosis
[30:05] the whole time? Because people often say
[30:07] when you talk about the ketogenic diet
[30:08] that it's not sustainable. Yeah. I I
[30:11] hear that a lot, but I have thousands of
[30:13] patients that have been doing it for
[30:14] years.
[30:15] And what happens is uh
[30:18] as soon as they
[30:19] exit from the ketogenic diet
[30:21] and they start to feel the trash build
[30:23] up again, meaning the joints that didn't
[30:25] hurt forever now hurt. The vision that
[30:27] was super clear is now foggy again. The
[30:30] brain that wasn't irritable and
[30:31] depressive is back to doing those things
[30:34] again. I mean, it is within a week or
[30:35] two that
[30:36] I mean, I like to think of
[30:39] when you're in a ketogenic state, you
[30:41] ring out that inflammation and trash in
[30:43] their brain, and the brain is like
[30:45] crisp. It is doing a great job.
[30:48] And when you put the sugar back in, the
[30:50] swelling goes back into their brain.
[30:51] Insulin and water flood the body, and
[30:54] it's almost like a minor concussion.
[30:57] And their brain is not working right,
[30:59] and they now know it. And is there any
[31:02] other benefits to being in a ketogenic
[31:05] state? You mentioned strength briefly.
[31:07] Yeah. So, when you're looking at do you
[31:09] do weightlifting? Yeah. Okay. So, when
[31:11] you weightlift
[31:13] how's
[31:14] grade your soreness on the day after
[31:16] your
[31:17] like lifting day? Um if I've been using
[31:21] that muscle consistently, there's no
[31:22] real soreness. Good. So,
[31:24] let's just take a day where you're
[31:25] pushing it harder. You're deadlifting
[31:27] harder, and you've got a strain in those
[31:29] muscles. One of the key components for
[31:31] repairing that as quickly as possible
[31:33] is
[31:35] is to be in a ketogenic state, to take
[31:36] that inflammation way down.
[31:38] And you probably didn't need the help of
[31:41] repairing that muscle when you were, you
[31:42] know, 18, 22, but as you get into the
[31:45] 30s, and especially into the 40s, the
[31:47] amount of inflammation
[31:49] that tries to help you repair that, it
[31:52] overshoots.
[31:54] And that's where the chronic pain's
[31:55] from. That's where the delay in repair
[31:57] comes from. So, when I look at power and
[31:59] muscle training, I the first place I
[32:01] talk to my patients about it is
[32:04] how many days does it take you to get
[32:05] back to to feeling good after you've had
[32:07] an injury? Uh let's let's be on the side
[32:10] of a ketogenic setting where your
[32:12] inflammation is super low, and when you
[32:15] tear something, which you're going to
[32:17] tear things when you're lifting heavy,
[32:19] the repair part is so quick.
[32:21] The power is a little hard to talk
[32:22] about. If you want me to go there, I
[32:24] can. Uh
[32:25] Yeah, so is there is there going to be
[32:26] any impact on my my ability to train
[32:29] Yeah. if I'm in a ketogenic diet? Am I
[32:31] going to be impacted in terms of
[32:33] endurance or strength or power or
[32:35] anything like that? So, we looked at
[32:37] this in um
[32:39] in military people. Uh it's one of the
[32:40] my favorite ones where they are all
[32:42] insulin resistant. And we put them on a
[32:44] ketogenic diet, and so they're trying to
[32:46] meet the standards. And at a month of
[32:49] being in a ketogenic state, they've lost
[32:51] weight, but their power and time didn't
[32:55] do anything too sexy.
[32:57] Then you look at those same soldiers at
[32:59] a year or I think it was 6 months was
[33:00] the next time they did another big
[33:01] check. Uh and by golly, they've lost
[33:04] even more weight, and their power is
[33:06] about 20% more than their counterparts.
[33:11] When they get to 18 months of a
[33:13] ketogenic diet, their power is almost
[33:15] 50% more than what their counterparts
[33:18] were. So, let me explain that. As you're
[33:20] looking at a muscle, it will choose
[33:23] which fuel it wants to use. And when
[33:25] you've been glucose using when you're on
[33:26] a non-ketogenic diet, it's going to use
[33:28] glucose first to fuel.
[33:30] But if you can train it to to use fat
[33:33] in that training, it's a longer, better
[33:36] fuel with less inflammation, and um
[33:39] especially in a a state where
[33:42] it will use both fuels quickly.
[33:44] That takes time. I mean, it takes And
[33:47] what I tell patients is, you'll love me
[33:48] in 18 months. You'll think I'm pretty
[33:50] great at 6 months. But if you're trying
[33:52] to run a marathon and we're only 3 to 4
[33:54] weeks out, you should not start a
[33:56] ketogenic diet. You're going to think
[33:57] it's the worst thing ever. It's meant to
[33:59] train muscles to use fat, and that takes
[34:02] time.
[34:03] And is there a link between some of
[34:05] these cognitive
[34:07] degeneration diseases like Alzheimer's,
[34:10] dementia, etc. and the ketogenic diet?
[34:13] Cuz I know that there's been some
[34:15] research that's underway and has been
[34:18] done to try and establish causality of
[34:20] Is there a link here? Yeah, you know,
[34:22] it's one of the saddest places where if
[34:24] you look at what patients regret in
[34:25] life,
[34:26] they come into the clinic, and they're
[34:28] already starting to say, "I was driving
[34:30] the other day, and I I got lost.
[34:32] And when I hear that, we are 15 years
[34:34] too late. It is 15 years of building up
[34:37] trash in that brain that we have to
[34:38] clean out that debris.
[34:41] And I had the privilege of an amazing
[34:43] story that taught me I don't have the
[34:46] gift of, you know, seeing into the
[34:47] future. Am I going to reverse these
[34:50] Alzheimer's before they show up? We
[34:52] don't have the research for it. Um but I
[34:54] have a lot of clinical experience
[34:56] saying, "Boy, they are so much better."
[34:59] I don't know if their memory is going to
[35:00] stay this good. We're only 3 years into
[35:02] a ketogenic diet, but it's way better
[35:04] than when it started.
[35:06] And then I had a Down syndrome patient
[35:11] at 40 years old
[35:13] uh in my practice.
[35:14] So, her mother came to see me first. She
[35:17] said, "I I want to try this ketogenic
[35:19] diet. Um I've been helping my daughter
[35:22] who's has Down syndrome. We've lost 100
[35:25] lb uh because the doctor said that she
[35:28] might do better
[35:30] if um if we lost some weight."
[35:32] And it's not an uncom- uncommon thing to
[35:35] see they have advanced insulin
[35:37] resistance and advanced Alzheimer's
[35:40] earlier in life. So, it's a great uh
[35:42] place to study Alzheimer's because they
[35:45] have a a more rapid onset of it. So, the
[35:47] woman comes, she's lost 100 lb, and
[35:50] during that time her mental cognition
[35:52] got worse.
[35:54] So, now she's got 100 lb down, but none
[35:56] of those brain things are better.
[35:59] And I said, "All right, if we're going
[36:00] to do this with your daughter, we're
[36:01] going to make sure we're pricking your
[36:02] finger. It's not going to be fake. We're
[36:04] going to do a real ketogenic diet."
[36:06] So, the mom starts on a ketogenic diet,
[36:08] and I think both her and mom are
[36:10] genetically super powered to make
[36:11] ketones cuz they have ketones of like
[36:13] three within a couple of days. Which is
[36:16] the average would be
[36:17] >> Like one. If I If they hit one in a few
[36:19] days, I'm thinking, "Good job." And the
[36:20] mom calls me at the end of the week
[36:21] saying, "Do you think it could possibly
[36:23] work this fast?" She is She's, you know,
[36:26] doing the little jobs that she used to
[36:28] do around the house. And I said, well,
[36:29] call me again in a week. Let's see how
[36:31] she's doing.
[36:32] And the mom goes, the most profound
[36:34] thing just happened.
[36:35] I've taken care of this girl for 41
[36:38] years.
[36:39] And I asked her the other day if she was
[36:40] doing something. She wanted to go to the
[36:42] church with me, which means she left the
[36:43] house.
[36:44] And she was at the church and she was
[36:46] giving her instructions to do this, go
[36:48] around here and put it over there and
[36:50] give her a little job.
[36:52] And she said, do you understand? And the
[36:54] girl replied, I understand.
[36:58] I said, what's the big deal?
[37:00] And the mother said, she had never said
[37:03] a three-syllable word in her whole life.
[37:06] Two syllables is all her brain could
[37:08] ever put together. For the first time in
[37:10] her whole life, 3 weeks on a ketogenic
[37:12] diet.
[37:13] And this Alzheimer's
[37:15] diagnosed patient who had Down syndrome
[37:19] now had a brain that was not only
[37:20] working great,
[37:21] it was doing the best mom had ever seen
[37:24] it. And on a ketogenic diet, not only
[37:26] did she lose about 15 to 20 more pounds,
[37:28] but her world opened up again because
[37:30] her brain, which had Alzheimer's, no
[37:32] longer had that diagnosis.
[37:34] I was looking at some of the supporting
[37:36] studies around this, around the impact
[37:38] that can have on the brain. And studies
[37:40] show that in dementia, especially in
[37:42] Alzheimer's, the brain struggles to use
[37:43] glucose efficiently. Ketones provide an
[37:45] alternative clean fuel source.
[37:47] Um ketogenic diets can boost
[37:49] mitochondrial function and energy
[37:50] availability in brain cells. Keto lowers
[37:52] systemic inflammation, which is linked
[37:54] to slower cognitive decline.
[37:56] Um
[37:57] ketones may protect neurons from damage
[37:59] and promote the growth of new neural
[38:00] connections. And Alzheimer's is
[38:02] something called type 2 diabetes, which
[38:03] I've had a lot um and keto improves
[38:05] insulin insensitivity, potentially
[38:07] reducing this risk. And lastly, small
[38:09] studies show temporary improvements in
[38:11] memory and cognition in people with mild
[38:13] cognitive impairment or early
[38:14] Alzheimer's, but the evidence is early
[38:17] stage. Long-term adherence can be hard
[38:19] and the diet isn't suitable for
[38:21] everyone.
[38:22] Uh for example, underweight people um
[38:23] and people with certain medical
[38:25] conditions. Right. So, how do I measure
[38:28] my blood ketone levels? Uh, is that what
[38:30] are these devices are here on the table?
[38:31] >> Yeah. I mean, when I look at um uh
[38:34] giving patients the freedom to say don't
[38:36] don't come to me for the things that I
[38:38] that you can do at home.
[38:40] First thing is be willing to check data.
[38:42] Okay.
[38:42] >> Okay? So, blood way better than any
[38:44] other way to measure this. We're going
[38:46] to be able to see Should we have a
[38:47] contest which one's better? Yeah. Okay.
[38:49] Okay? So, you want to go first? Okay.
[38:51] So, what I'm going to do here is I have
[38:52] a
[38:53] finger prick here which is going to take
[38:54] some blood. Just going to prick my
[38:55] finger. Then I have this little reader
[38:57] and I also have this little strip here
[38:59] which I'm going to put my blood on to.
[39:01] And within a couple of seconds, it's
[39:04] going to tell me how many ketones I
[39:05] currently have in my body right now. And
[39:08] so, we're going to look at that at the
[39:09] same time as your blood sugar, which is
[39:11] how you can measure insulin. It's the
[39:14] best proxy for saying how high is his
[39:17] insulin. So, put both of them in there
[39:18] before you go cuz then you don't have to
[39:20] just prick yourself twice. Okay. So, A
[39:21] blue one is going to measure the ketones
[39:23] and a brown one is going to measure your
[39:25] glucose.
[39:27] Okay. And this device, how much does it
[39:28] cost if people want to buy it at home
[39:29] and start pricking their own Yeah, I
[39:30] think there's a kit that comes with
[39:32] about 50 strips so you can have ketones
[39:35] and glucose at the same time. I'm
[39:37] guessing it's around 70 bucks or maybe
[39:38] it's 60 or 70 dollars. I They have quite
[39:41] the Now, put it all in. There you go.
[39:43] And so, they'll still It'll lights on
[39:44] the other one, too, right? Perfect.
[39:46] Okay. So, prick your finger.
[39:47] Best to do it on the side of your finger
[39:49] cuz there's less nerves there.
[39:51] There you go. Good job.
[39:54] Okay. So, I'm going to put my blood onto
[39:55] this one, which is the keto reader.
[39:59] And it'll it'll count down
[40:01] uh see I think it's about
[40:05] My glucose is 86.
[40:08] Takes more blood for the keto one.
[40:10] And my keto levels are 0.9.
[40:13] >> 0.9. Okay. So, that's a Dr. Boz's ratio
[40:16] of 86 / .9, which is probably like 95 or
[40:20] something, like 90
[40:22] five-ish, right? So, my glucose level's
[40:24] at 86. Is that high or low? That's good.
[40:27] Uh so, I would say that's not low, it's
[40:29] just good. Okay, and my ketone level's
[40:31] at .9. Right. So, when you look at them
[40:33] in comparison, like you want to have a
[40:35] blood sugar that's
[40:37] not triple digits, so that's very good.
[40:39] And the closer the higher you are above
[40:42] .5, the better the result. So, that's a
[40:44] pretty good number. So, if I'm in
[40:46] ketosis,
[40:47] >> Mhm.
[40:48] what reading would I have on this ketone
[40:50] meter? .5 or greater, but it would be
[40:52] also that you have that reading without
[40:55] a triple-digit blood sugar. So, when I
[40:57] look at the combination of them, I do a
[40:59] little math and say, "Your Dr. Boz ratio
[41:00] is like 95." So, you are burning fat
[41:03] right now.
[41:04] Okay.
[41:04] >> Okay? So, that's a good sign. When I am
[41:06] trying to help people who are trying to
[41:08] undo cancer or autoimmune or brain
[41:12] injuries, they have to have a better Dr.
[41:14] Boz ratio than that. Let's do your
[41:16] readings to see where you're at.
[41:19] All right.
[41:21] Drum roll.
[41:23] 83
[41:25] and 1.7. How are you at 1.7? What have
[41:28] you done?
[41:29] So, I've learned
[41:32] I would love to be 33 again and be able
[41:35] to eat that late at night.
[41:37] You said that I'm like, "Oh, it's been a
[41:38] while since I've eaten that late at
[41:39] night." It's probably the hardest thing
[41:41] to teach my patients too is like, "You
[41:43] don't appreciate how much insulin you
[41:45] make that late at night." Now, you're
[41:46] still in season where you get to just
[41:49] kick your heels and enjoy youth. But, at
[41:52] my age, you cannot do that. I can eat in
[41:54] the morning. I can have good calories of
[41:57] high fat and good protein in the
[41:58] morning.
[42:00] And I've learned to stop eating
[42:01] somewhere around 3:00 in the afternoon.
[42:03] Um in fact, if I Yeah, I know.
[42:05] >> 3:00 in the afternoon, you stop eating?
[42:07] That's usually the case. You know, what
[42:09] what's really hard though is how much of
[42:11] your life is social. Like you said, "Oh,
[42:13] there was this dinner party last night
[42:14] and I had pasta."
[42:16] And you're like, "Yep, uh that would be
[42:18] something I have to teach my patients.
[42:20] You have to say no to that. You cannot
[42:22] be eating at 10:00 at night if you want
[42:24] your insulin to not
[42:26] to not do that debris thing. And boy,
[42:29] when their memory isn't going well, when
[42:31] their friends are dying of uh memory
[42:33] problems,
[42:35] you know, it's I don't like using fear
[42:36] tactics. I don't think they last very
[42:37] long. But it is such a reality
[42:41] of poor performance that
[42:43] I can't do that. I cannot eat at 10:30
[42:45] at night. What is it about being asleep
[42:47] that causes the sort of dysregulation?
[42:51] Like, what is it about it doing it at
[42:53] night? So now it's going to take that
[42:54] metabolic curve and in order to
[42:57] to store all of the part that gets
[42:59] stored and then turn the part into fat
[43:01] that needs to be tucked away and get
[43:03] back to baseline, it's going to be 8
[43:05] hours, at least 8 hours.
[43:06] >> Which is fine. Right.
[43:07] >> Because I don't eat till I'm probably
[43:09] not going to eat till 2:00 p.m.
[43:10] >> Right. Well, you you missed one part.
[43:12] The sun will rise.
[43:14] When the sun rises,
[43:15] even if you're in solitary confinement,
[43:18] you cannot see the sun. Yeah. Your brain
[43:20] knows that the sun just went up and
[43:21] cortisol rises. Okay. Cortisol leaves
[43:23] your brain, goes to the liver and says,
[43:25] "You know that stored sugar, that
[43:27] glycogen, release."
[43:29] You make glucose first thing in the
[43:31] morning.
[43:32] How much glucose? Depends on how insulin
[43:34] resistant you are.
[43:35] So you're going to you're going to have
[43:37] an uneaten meal
[43:38] when you wake up in the morning. Glucose
[43:41] has been stored for the this purpose.
[43:42] It's going to wake you up. It's going to
[43:43] give you the energy when sun rises to to
[43:45] fuel you.
[43:47] If you got a bunch stored,
[43:49] you're going to have a high blood sugar.
[43:50] Can we do Jack's ketone levels? I'd like
[43:52] to know what what Jack is at.
[43:53] >> Ooh, let's do that.
[43:55] What's Jack do for a
[43:57] for his We're about to find out. I don't
[43:59] think I'm going to No, wait a minute. Is
[44:00] Jack the one that did the VO2 max with
[44:03] Peter Attia? That was me.
[44:05] Well, you know, peak brain performance
[44:06] is my thing and one of the hardest
[44:08] brains to heal are chronic runners.
[44:10] That trauma thing is real. Like, it's so
[44:13] hard to explain to them, too. If you're
[44:14] a vegan who runs, ooh, you're in
[44:16] trouble.
[44:18] 95% of vegans that listen to this
[44:20] podcast frequently don't subscribe.
[44:23] All right, so his glucose is 88, not too
[44:25] bad.
[44:26] Ketones, boo. Absolutely. Yeah. That's
[44:29] an example of he is making trash.
[44:32] There's no trash going out. So, his
[44:34] ketone level is what .1 and his blood
[44:36] sugar is 88. So, if you take 88 divided
[44:39] by .1, it's like what, 1,000 or
[44:41] something? It's really high. 888,
[44:43] probably.
[44:44] That is a lot of trash being made. When
[44:48] that Dr. Boz ratio is high,
[44:50] you can't take it out.
[44:52] >> to say that to his face? I mean, I feel
[44:53] like
[44:54] I just think that when Peter Attia did
[44:57] that and said, "Oh, I had no idea." I'm
[44:59] like, you could have just checked this
[45:01] first thing in the morning for 5 days.
[45:03] If you have that kind of a Dr. Boz
[45:04] ratio, you're insulin resistant. You're
[45:06] insulin resistant. You have to be
[45:08] hitting that in a routine regular
[45:10] interval in life to not have those
[45:12] problems. To have osteoporosis at such a
[45:15] young age,
[45:16] a ketogenic state would not allow that.
[45:18] You would be using the resources much
[45:20] better.
[45:21] He actually did a test, it turns out he
[45:22] doesn't have osteoporosis. Oh, good. But
[45:24] that was
[45:25] >> shocking. Yeah. I was like
[45:27] You shouldn't have osteoporosis at your
[45:28] age. No, I think that was a misreading
[45:30] because of this kind of um Right.
[45:32] >> But on this on this point in particular,
[45:34] his ketone levels are 0.1. So, he's
[45:36] basically running off glucose.
[45:37] >> All glucose. And and so, why is that
[45:39] happening? Okay, whatever he ate, the
[45:41] insulin went up. So, let's say he was
[45:43] your exact same eating pattern. He ate
[45:45] last night, he had the 6-8 hours of
[45:49] sleep, the cortisol said, "Oh, the sun's
[45:51] rising." And it rose his blood sugar a
[45:53] little bit. Okay, when the sugar's high,
[45:55] you can't you can't your insulin's going
[45:57] to be high, too. You're not making
[45:59] ketones. When I did these this keto test
[46:01] with most of the team here. They were
[46:03] all around that region. They were were
[46:05] in the region of 0.1 ketones in their
[46:07] blood to 0.3. Welcome to my clinic in 10
[46:09] years.
[46:10] That is trash being made, never being
[46:13] taken out. And so you'd say to them, you
[46:15] need to do some fasting, you need to You
[46:18] need to cut carbs. Yeah. I mean, if
[46:20] you're looking for a quick Okay, if
[46:22] they're in their 20s, I mean, I have
[46:23] three kids, right? And they have heard
[46:25] this chirp for 10 years.
[46:27] Uh I mean, how I got into this was my
[46:29] mother was very sick and she was sick
[46:31] because of a high insulin problem
[46:34] that caused cancer.
[46:35] So, we put her in a ketogenic state and
[46:37] everybody in the family got on board.
[46:39] So, here is three little boys who no
[46:40] longer have candy around. Now they're in
[46:42] their young 20s and for the first time
[46:43] they're actually listening to say,
[46:45] "Gosh, Mom." One of them's at
[46:46] Georgetown. He has to read for long
[46:48] periods of time for Georgetown Law
[46:49] School.
[46:50] And he's like, "If I'm not in a
[46:52] ketogenic state,
[46:53] I can't keep the focus." And I said
[46:57] Yeah, I said, "Well, how are you doing
[46:57] that?" At first, he tried some of the
[46:59] supplements, okay. But what really
[47:01] happened was he cut the carbs down and
[47:03] said, "I can say no to that because of
[47:06] the sustained brain power." I mean, it's
[47:07] really easy in your early 20s to do
[47:09] this. Cut the carbs even to 50.
[47:11] But prove to yourself that you made
[47:13] ketones and that return on your
[47:16] dividends is you won't be seeing me in
[47:18] 25 years. So, you have this idea of this
[47:20] keto continuum. Mhm. What is the ketone
[47:25] continuum? I read about it. I mean, it's
[47:27] it's a book here I have which you
[47:29] published in 2020
[47:30] called The Ketone Continuum Consistently
[47:32] Keto for Life. Right. So, the keto
[47:35] continuum is this 12-step process Right.
[47:38] to get into a consistent keto
[47:40] >> Consistently keto. Yeah, that you're
[47:41] constantly taking out the trash. The
[47:43] first part is the beginner. Okay, so the
[47:44] first part, the beginner section, has
[47:46] four stages to it. Right. What are What
[47:48] are those four stages? Well, I like to
[47:51] tell patients that you never fall all
[47:52] the way off of the continuum. So, the
[47:54] first part the first step is really not
[47:56] keto, but it is that they're eating
[47:58] every two to three hours and if they
[48:00] fall off the wagon, that's usually where
[48:01] they land. So that's what most people
[48:02] start at. They're eating every two to
[48:03] three hours, they are not keeping their
[48:05] carbs less than 20. Step two is cut your
[48:08] carbs to 20. That's the only thing I
[48:11] need you to measure and you're going to
[48:13] be able to use a ketone strip, you know,
[48:15] measure ketones in your urine
[48:17] uh and that will ride you'll you'll ride
[48:20] a wave
[48:21] and that ketone production is happening,
[48:23] the fat-based hormones in your body are
[48:26] starting to resurrect, they're starting
[48:27] to do the things that they need to do
[48:30] and there'll be this magical moment in
[48:32] the not too near future
[48:35] where you skip a meal.
[48:36] And this that beginning stage
[48:39] how long does that last? I'll put this
[48:41] on the screen so everybody can see Sure.
[48:43] the continuum. Um how long does that
[48:45] initial beginner stage last for people?
[48:47] If they've been severely insulin
[48:48] resistant, this is the ones where I've
[48:50] said they took their carbs to 20 for for
[48:54] two weeks before they pee'd a ketone.
[48:56] So I use some other steps if that's how
[48:58] severe that is. But let's just take the
[49:00] average person. That's like not they're
[49:02] not 100 lbs overweight, they're hitting
[49:04] menopause and they've put on 25 lbs.
[49:06] When they drop their carbs to 20,
[49:08] they're peeing a ketone by the end of
[49:10] the week and they are missing their
[49:12] first meal by day 10. Okay, so day 10.
[49:16] And then it says when we get to stage
[49:18] five in the keto continuum, it says 16
[49:20] 80 16 8. Is that Yeah. So then we start
[49:23] to use time-restricted eating uh where I
[49:26] want we we're going to have your body
[49:28] will adapt. People say you can't stay on
[49:30] the keto diet because they go to step
[49:32] four and then they think that that's all
[49:33] they needed to do. There are several
[49:35] steps to reversing this problem and
[49:37] you'll know you have the right step if
[49:38] the ketones are still present in your in
[49:40] your blood.
[49:41] Your body will adapt though. So we start
[49:43] to say, all right, we're going to learn
[49:45] some new behaviors.
[49:47] We're going to learn what the nothing
[49:48] burger looks like at least for 16 hours
[49:51] out of the day. What does that mean? You
[49:53] do not eat a thing in those 16 hours.
[49:56] Now,
[49:57] I give them a little hedge because most
[49:59] people come in like you. They don't
[50:00] start eating until 2:00 in the afternoon
[50:02] and then they eat until 10:00.
[50:04] And I want them fat forward. I want lots
[50:07] of fat going in because insulin
[50:10] resistance,
[50:11] that high insulin state, means they've
[50:14] locked or they've insulated their fat on
[50:15] their body. And then we get stage seven
[50:17] where it says 23:1. Is that fasting for
[50:21] 23 hours a day and eating for 1 hour a
[50:22] day?
[50:23] >> And the there's a little bitty line
[50:25] between 16:8 and 23:1,
[50:28] but there's a whole bunch of life there.
[50:30] Meaning, we don't actually have patients
[50:32] go from 16 hours of fasting
[50:34] to 23. We have them slide it down by an
[50:37] hour, slide it down by an hour, and then
[50:39] we do that harder thing which is
[50:41] move it towards sunrise. Quit eating so
[50:43] late at night. And then the last stage
[50:45] here,
[50:46] so so step nine, 10, 11, and 12 is
[50:50] prolonged fasting between 36 and 72-hour
[50:53] fasting. Right. So, those folks that
[50:55] have high insulin for 20, you know, 15,
[50:57] 20 years,
[50:59] they're going to have to do a nothing
[51:00] burger for 36 hours in most of them to
[51:03] really give a good reset of their
[51:04] metabolism. And although you you look at
[51:07] other folks saying, "Oh, you should
[51:08] never do that if you're a woman. You
[51:10] should never do that over the age of
[51:11] 50." I'm saying you have too much
[51:13] insulin in your body. You have to do
[51:15] that to get the pancreas to make less
[51:17] insulin over time. On that point,
[51:19] between men and women, aren't there
[51:20] metabolic differences that need to be
[51:22] mentioned here? Because you know, when I
[51:24] sometimes when I do ketogenic fasting,
[51:26] my girlfriend, she takes much longer
[51:28] than me to get into a ketogenic state.
[51:29] And I'm wondering if her body is in some
[51:31] way trying to defend Mhm. the switch.
[51:34] >> Have you ever seen the the reality show
[51:36] Alone? Oh, no. I'm not a reality show
[51:38] guy. I'm not either, but they drop these
[51:40] people off in the middle of nowhere and
[51:41] they starve them to death. And you watch
[51:43] the fat come off of them. And the men,
[51:46] the fat just
[51:47] melts off of them. And the women, they
[51:50] do what your girlfriend does. It just
[51:51] holds on to them. That we are designed
[51:54] to have that fat on them. So, asking
[51:57] them to do a ketogenic state, you'll
[51:59] hear people say, "Oh, it's going to ruin
[52:00] your hormones. Oh, it's going to You
[52:02] can't do that." And um I would say you
[52:05] can have all those conversations once
[52:07] their insulin is normal. Well, I have
[52:09] lots of women in childbearing years that
[52:11] are excessive producers of insulin. And
[52:14] their vitamin D is low, their estrogen
[52:17] is low, they have hair loss on the top
[52:19] of their head, they have skin tags
[52:20] throughout their body, or maybe the
[52:22] first sign was they had PCOS.
[52:24] Okay, all of these are a sign that
[52:26] insulin came in and it's too high in
[52:28] their body. So, lowering it has rules.
[52:31] And if you want to have a baby, carry a
[52:33] baby, uh have uh the weight come off
[52:36] after you've gestated a baby, um have
[52:39] weight not be your enemy during
[52:40] menopause, you have to be making ketones
[52:43] at a routine and regular interval. And
[52:46] start with the food. Start with the
[52:48] menus in the kitchen.
[52:50] Don't run to the gym first.
[52:52] I've noticed uh in women in my life that
[52:54] they've told me that their menstrual
[52:56] cycles become more synced up when they
[52:58] are in a lower carbohydrate diet. Right.
[53:01] Their hormones can hear each other. I
[53:03] mean, when insulin is high, insulin
[53:05] dictates what that sugar does, but it
[53:07] also is the dictator for every morsel of
[53:10] fat.
[53:11] And estrogen, testosterone, vitamin D,
[53:15] they're all a derivative of fat, of
[53:17] cholesterol. And they are They're put
[53:19] into the fat cells. If you biopsy an
[53:22] obese woman and say, "Can I see is there
[53:24] any vitamin D hidden in there? Is there
[53:26] any estrogen? Is there any Yes, they're
[53:28] all in those fat cells.
[53:30] You start to lower their insulin and the
[53:32] fat mobilizes. So, the hormones that are
[53:34] naturally communicated between women,
[53:37] they can actually hear them again. I
[53:38] mean, that that tribal thing. If a woman
[53:40] were to stay in a ketogenic state
[53:42] permanently,
[53:44] would there be any disruption to her
[53:46] metabolic health? You mean like me?
[53:48] Yeah. Like you know, her menstrual
[53:51] cycles, her
[53:52] uh yeah, anything.
[53:54] >> No, I think it's
[53:56] You're going to find people that it
[53:57] shouldn't be extreme, meaning I've been
[54:00] on this for 15 years. The ketogenic
[54:03] phase is at least 20 out of 30 days
[54:07] uh in a month the first few years I was
[54:09] on it. Now at 55 uh menopause in the
[54:12] last year um I'm like without a ketone,
[54:16] my brain doesn't work right now without
[54:17] a ketone. Uh my energy goes to pot. And
[54:20] I've been walking women through
[54:21] menopause for 25 years. It is not a fun
[54:24] story when they're insulin resistant.
[54:27] So, prepare. Uh have the flexibility of
[54:31] that mitochondria to use both ketones
[54:33] and glucose, and that's what a ketogenic
[54:35] state is. Well, we have 12 cans of
[54:37] sardines here, and uh I I I wondered why
[54:41] you you brought sardines. What you
[54:43] >> Well, yes. That's a hell of a tool.
[54:47] Why?
[54:48] So, um when you're trying to help
[54:50] patients change behavior,
[54:55] Sorry, the sardine juice has gone on my
[54:56] iPad.
[54:58] Uh good luck getting that off.
[55:00] Yeah, sardines rank for
[55:02] uh the worst smelling, but they're not
[55:04] the worst tasting.
[55:06] Now when it comes to bitter in fish,
[55:07] they don't have the bitterness that tuna
[55:09] does. So. Tell me about sardines. Why
[55:11] why should I be eating sardines? When
[55:13] you're trying to teach patients, those
[55:14] stats that you read off a minute ago,
[55:16] they don't care. They need a very clear
[55:18] step on how do I begin.
[55:20] And when you're working with somebody
[55:22] who cannot seem to get their ketones to
[55:24] rise, and I give them a whole list of
[55:26] menus, it's too noisy. Let's take it
[55:28] down to one food that is high in fat,
[55:31] high in some of the best fats, high in
[55:33] protein, it's whole foods, and it's
[55:35] affordable for everybody under the sun.
[55:38] Okay, so you do you do you like a
[55:40] sardine fast? Yeah. So in fact that that
[55:43] 21-day we 21-day is that 3-week course
[55:46] where I say I will teach you how to do
[55:47] an advanced ketogenic diet where
[55:49] everybody will be peeing key or making
[55:51] abundant ketones.
[55:53] On day six uh I say all right, the only
[55:56] thing on the menu for the next 3 days
[55:58] is sardines.
[56:00] There's no eating window. You can eat as
[56:01] much as you want. There's no limit to
[56:03] the amount. And what I'm pushing them to
[56:06] do is not only eat a nutrient-dense
[56:08] food, but I want them to feel satiety. I
[56:10] want them to feel full. Do I need to be
[56:13] consuming a lot of fat as well? There's
[56:15] plenty of fat in there. But I mean
[56:16] generally cuz what this is one of the
[56:17] the fat Yeah.
[56:18] >> things that always puzzles me is I'll
[56:20] I'll go
[56:21] say I went a week without eating
[56:23] carbohydrates.
[56:26] Sometimes I'm still not in ketosis. And
[56:27] I think I heard somewhere that it's
[56:29] because my fat Right. So
[56:31] >> enough. So Yeah. So again, at the time
[56:34] you went you went 7 days without eating
[56:36] hardly any carbs, right? And you still
[56:37] didn't make a lot of ketones. Okay. So
[56:39] you had fat on your body?
[56:41] Yeah. Okay. So why didn't the fat get to
[56:43] your mitochondria?
[56:45] Excess insulin. Okay? You had been in a
[56:47] high insulin state. So if you swallow
[56:50] the fat, then you can turn it into
[56:51] ketones. Right now all your fat's locked
[56:54] under this insulin bed. If you kept
[56:55] going, it would eventually hit, but
[56:57] that's painful. I mean I have patients
[56:58] who do it for 2 weeks. So what you're
[57:00] saying? You're saying that I need to
[57:01] have enough fats?
[57:02] >> Yeah. So if you put the sardines in oil,
[57:05] uh that's a great high-fat,
[57:06] high-protein.
[57:08] Uh it's also a little easier to
[57:09] masticate the the meat. And you'll have
[57:12] high-fat, high-protein, and you'll have
[57:15] beautiful ketones by by 48 hours, maybe
[57:17] 72. And what what is the the composition
[57:20] of my diet in terms of protein, fats,
[57:22] and carbohydrates when I'm trying to get
[57:23] into a ketogenic state? Yeah, I don't
[57:26] let people get distracted by this,
[57:27] right? I say look at your finger. If
[57:30] it's got a high ketone, you have got
[57:32] enough fat and enough protein uh
[57:35] and low enough carbs. What most people
[57:37] have is the story you told. I've been
[57:39] doing this for 5 days. Why don't I make
[57:41] any ketones? And the answer is what is
[57:44] hidden behind the chemistry is too much
[57:46] insulin.
[57:47] You've got to have and so that's a great
[57:49] place to say put the fat up, keep the
[57:51] carbs low and the ketones will come.
[57:54] When you say put the fat up, you mean
[57:55] eat more fatty foods. Give me an example
[57:57] of the type of shopping list that if I
[58:00] was trying to get in a ketogenic state
[58:01] and stay there,
[58:03] I would have. Yeah, my one of my
[58:05] favorite things is
[58:06] pork belly,
[58:08] more eggs,
[58:09] beef brisket, ribs. Avocado? Avocado
[58:12] have beautiful marketing team, but they
[58:15] do have carbs in them and I've had
[58:17] people overeat them. Like I have four
[58:19] avocados today. I'm like, that's
[58:21] you're on the wrong bandwagon there.
[58:24] Avocado makes the list, don't get me
[58:25] wrong, but it's not a diet of mostly
[58:28] avocado with a sprinkle of chicken
[58:29] breast. That's not going to get you into
[58:30] ketosis. The fat has to be higher than
[58:32] that. Most of the time when I'm really
[58:34] struggling with a patient who just can't
[58:37] seem to make ketones, can't seem to make
[58:38] ketones and they won't do the sardines,
[58:41] I've said eat butter for a day. That's
[58:43] 100% fat.
[58:45] Okay, so you can just have increase the
[58:46] butter or Yeah, you could have that.
[58:48] Okay, so that Are there carbs in here?
[58:50] No. No. No, it's just fat. Mhm. Mhm.
[58:54] And it's not awful,
[58:56] but it is a great social experiment
[58:58] where they haven't felt what satiety
[59:00] feels like in a while. People talk about
[59:02] net carbs. They say, you know, an
[59:05] avocado has
[59:06] 12 g of carbs in, but it has 10 g of
[59:09] fiber, so the net carbs is two. If
[59:13] you've never had insulin resistant, you
[59:14] can do it that way. My patients have had
[59:16] high insulin and I don't play that game.
[59:18] It's got to be total carbs.
[59:21] Fiber is for farting.
[59:22] Do you recognize this photo
[59:25] of this lady?
[59:27] Oh, yes.
[59:28] Who is she?
[59:29] >> Why, she is just a great story. Jane had
[59:32] uh
[59:34] uh she had pathology with how she
[59:36] thought about food. Like many patients.
[59:38] She
[59:39] uh she had food as the way she coped
[59:41] with a lot of things. And as long as she
[59:44] was clearing her plate and using that
[59:46] food, it covered a lot of wounds.
[59:49] When you start to address some of these
[59:51] things, I mean, the ketogenic diet
[59:52] doesn't fail if you just follow the
[59:54] chemistry. The ketogenic diet fails when
[59:56] you have humans who've had wounds,
[59:59] who've had a history, who have stress,
[01:00:01] who don't sleep.
[01:00:03] And Jane was a great story where
[01:00:05] all the goodness in the world it
[01:00:07] couldn't undo some of that relationship
[01:00:09] she had with food.
[01:00:11] Uh so, the first time she one of the
[01:00:12] coaches that I used for that 21 day, and
[01:00:15] she just has the best outcomes cuz she
[01:00:17] was doing the a strong ketogenic diet,
[01:00:19] you know, for those 3 weeks twice a
[01:00:20] year.
[01:00:21] And she decided that after I think the
[01:00:23] third class, she was going to do
[01:00:24] sardines only for 30 days.
[01:00:27] And she writes me at the end of the 30
[01:00:29] days, can't believe how great she feels.
[01:00:31] And really kind of addressed some of
[01:00:33] those demons associated with why she
[01:00:36] would eat what she would eat.
[01:00:37] And then life hit again, and she put on
[01:00:39] some of the weight again. Um she'd used
[01:00:41] sardines intermittently. And she called
[01:00:43] me and said, "All right, I think I'm
[01:00:44] going to do this again. I'm going to
[01:00:45] just go on sardines and really have a
[01:00:48] some come to Jesus moments on why it why
[01:00:51] it is that I do some of the things I
[01:00:52] do." I mean, it's a really vulnerable
[01:00:54] moment where you can hide those moments.
[01:00:56] You can never tell a soul what's really
[01:00:58] going on through your mind, and she was
[01:01:00] going to address them.
[01:01:02] And I said, "Well,
[01:01:03] I have a bone to pick with Joe Rogan.
[01:01:06] He has said some
[01:01:08] inappropriate things about sardines,
[01:01:09] like they're arsenic poisoning. So, I'd
[01:01:12] like to check a few blood levels in you
[01:01:13] before you start." So, I check her
[01:01:15] vitamin D, we check her arsenic,
[01:01:17] selenium, and a few other things. And
[01:01:19] she starts on her sardine challenge her
[01:01:20] sardine journey, and she goes 100 days.
[01:01:24] 100 days of only sardines.
[01:01:27] And not only does she first of all, her
[01:01:29] vitamin D, she did not take any vitamin
[01:01:31] D, she stopped her vitamin. It went from
[01:01:32] like the 30s and 40s up to
[01:01:36] just maybe over 100, 108 or something.
[01:01:38] Uh her selenium didn't do anything
[01:01:39] naughty. Her arsenic did not do anything
[01:01:42] naughty like Joe Rogan said it would.
[01:01:45] And she was able to um
[01:01:48] not only shed the pounds, but really
[01:01:52] say some truths about why she was eating
[01:01:53] so much.
[01:01:56] And she confronted the pathology about
[01:01:59] why
[01:02:00] why is she using food for those other
[01:02:01] things?
[01:02:02] You know, I do this thing in the 21-day
[01:02:04] where I ask them to find their best day
[01:02:07] in their life.
[01:02:08] And I'm trying to just get them to think
[01:02:10] about what does that feel like? What did
[01:02:11] What did that look like?
[01:02:13] And then we go to the worst day in their
[01:02:14] life. And Jane wrote something that
[01:02:16] really touched me.
[01:02:17] She said, "I don't think I've ever had
[01:02:19] the best day of my life."
[01:02:22] This was probably the third or fourth
[01:02:23] time we'd done that exercise, so she'd
[01:02:24] done it in a way where
[01:02:26] it didn't bring any extra attention, but
[01:02:28] she was she spoke a truth that just
[01:02:29] said,
[01:02:31] "I've had this fear for so long
[01:02:34] that for the first time I'm going to say
[01:02:36] out loud that
[01:02:37] I'm looking for the best day of my life,
[01:02:39] and I feel like I have the freedom to do
[01:02:41] it."
[01:02:43] That's what happened after 100 days of
[01:02:44] sardines. So, if she eats sardines for
[01:02:47] 100 days,
[01:02:49] she's probably not going to get like the
[01:02:51] gut microbiome.
[01:02:53] She has the best gut microbiome.
[01:02:55] Doesn't she need to be eating plants to
[01:02:58] Oh, no. Fibers for farting.
[01:03:01] So,
[01:03:02] you're looking at a gut biome, right?
[01:03:03] And so, tell me what you think that is.
[01:03:06] Uh lots of bugs that have been feeding
[01:03:09] on plants.
[01:03:11] Okay, yes. Pooterate has uh has part of
[01:03:13] that equation. So, gut biome is the
[01:03:16] slime layer inside your gut. It's where
[01:03:18] the critters live. It's where they set
[01:03:20] up homes and they If you have a really
[01:03:22] good slime layer, it's squishy. It's
[01:03:24] dense. It's not moth-eaten. It's not
[01:03:27] aqueous or water-like. It's squishy.
[01:03:30] And when you put plants in there, when
[01:03:33] you put fiber in there, it tears that
[01:03:34] down. Uh and you say, "Well, fiber's
[01:03:37] needed for this because some of those
[01:03:39] bugs eat up on the fiber and they put
[01:03:42] out some butyrate and that helps these
[01:03:44] other bacteria to to grow." You're like,
[01:03:47] "Yeah, that's one way to get a good
[01:03:49] microbiome." But we haven't been fiber
[01:03:52] eaters forever. And when you look at
[01:03:53] many of my carnivore patients,
[01:03:55] especially when they've got, you know,
[01:03:57] some of those little fish scattered into
[01:03:59] that carnivore diet, um their symptoms
[01:04:03] of irritable bowel, of chronic diarrhea,
[01:04:06] of, you know, bloody ulcers
[01:04:09] reverse.
[01:04:10] Why? Cuz that gut biome got a lot
[01:04:12] stronger and a lot healthier. So, the
[01:04:15] things that I from doing this podcast
[01:04:16] for a long time, the things that I'd I'd
[01:04:17] be concerned about if I just ate
[01:04:19] sardines for a prolonged period of time,
[01:04:20] or really any diet, I guess, for a
[01:04:21] prolonged period of time, a narrow diet,
[01:04:23] would be
[01:04:25] the fiber issue we talked about. Um and
[01:04:28] then all the other things that are just
[01:04:29] not in sardines. I mean, vitamin C.
[01:04:31] Yeah, you still get a lot good vitamin
[01:04:32] C. So, vitamin C has different rules
[01:04:34] when you go carnivore. What about
[01:04:35] magnesium? Yeah, lots of that. Uh
[01:04:37] magnesium I still think is one of the
[01:04:38] supplements we all need. What about the
[01:04:40] sodium overload? Cuz these are very
[01:04:42] salty, right?
[01:04:43] >> Your sodium churn, how well you use
[01:04:46] sodium, is dependent on how well you've
[01:04:48] eaten in the last week. So, when you
[01:04:49] increase the sodium, those receptors get
[01:04:51] better. When you decrease the sodium,
[01:04:52] those receptors shut down. That's a That
[01:04:55] is an adjustment that everybody will
[01:04:56] make. What about things like mercury and
[01:04:58] the other sort of metal toxins?
[01:05:00] >> Little fish, little problems. You got
[01:05:01] the right one for mercury. Again, we
[01:05:03] tested that for her, too. 100 days, no
[01:05:05] problem.
[01:05:07] Are there especially in the can, as
[01:05:08] well? I
[01:05:09] I think I've got a bit of an issue with
[01:05:10] canned food these days because I've
[01:05:11] heard so many
[01:05:12] >> Microplastics. Microplastic toxins, etc.
[01:05:15] I think you're majoring in the minor
[01:05:16] leagues there.
[01:05:18] That the the amount of benefit that
[01:05:20] people get from sardines versus whatever
[01:05:23] might be in those in that can. I tell
[01:05:26] patients not to worry about it.
[01:05:28] And then the last point I said was about
[01:05:30] digestive and mood issues because the
[01:05:32] that microbiome is so So linked to
[01:05:34] brain, absolutely. Serotonin, isn't it?
[01:05:35] The the I mean serotonin is in the gut,
[01:05:37] but it's it's a huge part of like a
[01:05:39] GLP-1, GIP, they're all produced
[01:05:42] hormones in the gut that are hugely
[01:05:44] impacting your brain. And when you want
[01:05:47] GLP-1 to be made, have a strong thick
[01:05:50] microbiome. You do not need fiber to do
[01:05:52] that. You need butyrate.
[01:05:54] Butyrate is that two-carbon
[01:05:56] uh fat that comes from Akkermansia, you
[01:06:01] know, chewing up the fiber, right? Or
[01:06:05] beta-hydroxybutyrate
[01:06:06] in your blood.
[01:06:08] That's that ketone thing you're got over
[01:06:09] there.
[01:06:10] Oh. These things. Yeah, all of them.
[01:06:13] Gosh, I forgot.
[01:06:14] There you go, yes. Keto It's a
[01:06:16] beta-hydroxybutyrate is what that is
[01:06:18] going to turn into your circulation.
[01:06:19] Butyrate is a fat chain that's two
[01:06:22] carbons long.
[01:06:24] That's what the you're asking that
[01:06:26] microbiome to say, "Here, this long
[01:06:28] string of fiber is coming along." And
[01:06:30] that that little bug is going to eat a
[01:06:31] piece of it and make butyrate, two
[01:06:33] carbons of fat.
[01:06:35] That's one of these things that you're
[01:06:37] talking about. You need to have
[01:06:37] butyrate. You need to have butyrate.
[01:06:38] That's what every every Why are you even
[01:06:41] invited? You got to have butyrate. All
[01:06:43] these, you know, experts come on my show
[01:06:44] and they talk about the importance of
[01:06:45] having a diverse I know. I I've watched
[01:06:47] a bunch of them. Diverse microbiome,
[01:06:49] yes. And what I think
[01:06:51] >> So it's not going to be diverse if I'm
[01:06:52] just eating one thing. Oh, yes, it will.
[01:06:55] In the same way. You know, what So
[01:06:56] that's the whole point of a microbiome
[01:06:58] is what what, you know,
[01:07:00] diverse enough to be supportive. I mean,
[01:07:02] diverse enough to have the the two-chain
[01:07:05] fat that you want to have in there. I
[01:07:07] mean, go back uh
[01:07:10] and and look at when our bodies were
[01:07:12] just eating um you know, fish or
[01:07:15] carnivore. Uh
[01:07:17] they the beauty of a microbiome is how
[01:07:19] much it does adjust in
[01:07:22] every patient. What about
[01:07:24] supplementation? What are the key
[01:07:25] supplements that you
[01:07:28] don't live without on a daily basis?
[01:07:30] Vitamin D turns out to be a a really
[01:07:32] important one. I If I'm eating sardines
[01:07:34] uh four or five cans a week, I probably
[01:07:36] don't need vitamin D, but Why is it so
[01:07:38] important, vitamin D? Yeah, it's a
[01:07:40] hormone, right? A hormone that goes and
[01:07:42] talks to every one of the cells in your
[01:07:44] body
[01:07:45] and it tells that cell to be its best
[01:07:49] version of itself. That hormone uh goes
[01:07:52] to the nucleus and it makes that skin
[01:07:54] cell do something different. It makes
[01:07:56] your brain cell do something different.
[01:07:57] It makes your heart cell do something
[01:07:58] different. You read all the benefits
[01:08:00] about vitamin D and you think
[01:08:02] it's like
[01:08:03] it's like it does everything. Like,
[01:08:05] well, how can it do all of these things?
[01:08:06] And the reason why is it is not just a
[01:08:08] vitamin, it's a hormone that changes how
[01:08:10] the cell functions. Unfortunately,
[01:08:13] it's made of fat.
[01:08:15] So, if you have high insulin, it gets
[01:08:17] stuck parked in your fat cells and it
[01:08:19] didn't get to the cell. Is there a link
[01:08:21] between vitamin D and ketosis and weight
[01:08:24] loss and insulin? Yeah, it's actually
[01:08:26] why I pointed out that when Jane did
[01:08:27] that 100 day
[01:08:29] uh she's been struggling with her
[01:08:30] vitamin D it in the 30s or 40s. Right.
[01:08:33] But for the best brain, we want it to be
[01:08:35] a 50. So, she starts on the sardine
[01:08:37] challenge, it's in the 30s or 40s, and
[01:08:38] she's supplementing. She's taking as
[01:08:40] much as she can.
[01:08:41] But what's happening? Her insulin was
[01:08:44] putting it in her fat. She goes on
[01:08:45] sardines, which have vitamin D in them.
[01:08:48] By the end, her vitamin D was 105 108,
[01:08:52] something like that. So, you can see the
[01:08:54] experts say don't go above 100, but the
[01:08:57] I don't I don't have any worry over hers
[01:08:59] being 108.
[01:09:01] What happened was she lowered her
[01:09:03] insulin and now fat can move around in
[01:09:05] her body like it's supposed to. And part
[01:09:07] of that fat isn't just her estrogen. It
[01:09:09] was her vitamin D.
[01:09:10] She looks like 20 years younger. Isn't
[01:09:12] it amazing? You should see how joyful
[01:09:14] she is. That's the part that you're
[01:09:16] like, what unlocked during those 100
[01:09:18] days of you can say food restriction,
[01:09:20] but vitamin D went up,
[01:09:22] insulin went down, and she really said,
[01:09:26] "How many things am I going to comfort
[01:09:28] in my life from food?"
[01:09:30] And let's let's let's tackle that demon.
[01:09:32] Did it stick? Yeah, that's the cool
[01:09:34] part.
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[01:10:31] What are What about the other
[01:10:32] supplements that you would not live
[01:10:34] without? Well, I think the whole world's
[01:10:36] low in magnesium. I wish I could
[01:10:38] Magnesium? Yeah.
[01:10:40] So magnesium is required for every
[01:10:42] little
[01:10:43] It's like the spark plug in our bodies.
[01:10:45] It's a little metal, and it's how ATP
[01:10:47] gets recycled, and you need it for
[01:10:49] almost every enzyme. But our food is low
[01:10:51] in it, our foods our soil is low on it.
[01:10:53] You just got to replace it. I I use
[01:10:56] magnesium supplements, but I also have
[01:10:58] my patients go for a magnesium float.
[01:11:01] What's that? Uh ever seen pictures of
[01:11:03] people in the Dead Sea? No. Uh they're
[01:11:06] floating, right? This the salinity or
[01:11:07] the salt level is so high and it stinks,
[01:11:09] right? It's a stinky place. It's
[01:11:11] magnesium. So, they go in there, they
[01:11:13] soak in the magnesium and you're like,
[01:11:15] "Oh my gosh, I feel so much better."
[01:11:17] Like that's got to be junk science,
[01:11:18] right? Well, it turns out it's not. So,
[01:11:21] you can get magnesium absorbed through
[01:11:22] your skin and just like, I don't know,
[01:11:25] in the 1990s you'd go rent time in a
[01:11:26] tanning bed, you can rent time in a
[01:11:29] magnesium float. Any of this? So,
[01:11:32] omega-3, if you're not doing fish, uh
[01:11:34] you can't go wrong with omega-3. And you
[01:11:36] know,
[01:11:37] uh I Stephen, I really push my patients
[01:11:40] to have ketones around. What you When
[01:11:42] you say ketones, you mean external
[01:11:43] >> Exogenous ketones, yeah. So, what
[01:11:45] exogenous means external, externally
[01:11:47] consumed. There may be some on the table
[01:11:49] here. I'm an investor in this company,
[01:11:50] actually, so
[01:11:51] that's probably worth saying. Keto IQ.
[01:11:53] Um there you've got some other ones
[01:11:55] here, which are What's this? It's like a
[01:11:57] >> That's ketone salts. So, this one is
[01:11:59] just beta-hydroxybutyric acid. My
[01:12:01] husband is definitely allergic to
[01:12:02] stevia, so I said, "I'll make this one
[01:12:04] for you, honey." It's just liquid
[01:12:06] ketones. Okay. No No sweeteners, no
[01:12:09] fillers, nothing.
[01:12:10] >> And is there a difference between taking
[01:12:12] external ketones through a drink or
[01:12:15] through the salts or whatever else
[01:12:16] versus actually being in
[01:12:18] the ketogenic state because of your
[01:12:20] diet? When you make it, it is much more
[01:12:22] abundant. But when you do what people
[01:12:25] do, they fall off the wagon or they're
[01:12:27] very insulin resistant, so their body is
[01:12:29] trying to catch up to to equilibrate.
[01:12:32] You want ketones put back in circulation
[01:12:35] because it will spark their liver to
[01:12:37] make ketones. So, it really is a
[01:12:39] jump-start for patients with chronic
[01:12:41] insulin resistance, chronic problems. We
[01:12:43] got about, you know, 6 years of getting
[01:12:45] them to the healthiest version of
[01:12:46] themselves as long as they don't fall
[01:12:48] off the wagon. So, when they are
[01:12:50] doing okay and now they need to get back
[01:12:52] on the track. Give them a dose of
[01:12:54] ketones and by putting ketones in their
[01:12:56] circulation like that, by checking their
[01:12:59] blood, the liver will make ketones. So,
[01:13:01] it's not just a fuel, they will feel
[01:13:03] better.
[01:13:04] It's a signal for the liver to make more
[01:13:07] ketones.
[01:13:07] >> But I'm not going to be burning fat
[01:13:09] then, am I? You will. I mean, again,
[01:13:11] ketones beget ketones. When you are
[01:13:12] making ketones, your body makes more
[01:13:14] ketones. So, if you jump start it by
[01:13:16] swallowing some,
[01:13:18] you get better tomorrow, get a better
[01:13:19] tomorrow. And usually, if somebody's
[01:13:21] falling off the wagon, I'll have them do
[01:13:22] ketones for like 3 days and the fourth
[01:13:25] day they are on their own again and
[01:13:26] they'll stay steady for
[01:13:29] couple of weeks and then they'll have
[01:13:31] pasta.
[01:13:33] I I that's why I invested in this
[01:13:34] company because I'm actually a co-owner
[01:13:36] of the business now and because I saw
[01:13:38] the benefits of having exogenous ketones
[01:13:41] on a regular basis. Right. So, if anyone
[01:13:43] wants to try them, go to keton.com. And
[01:13:46] your brain will use it like that. I
[01:13:47] mean, it's beautiful, right? When I use
[01:13:50] my ketone reader, it appears in about 15
[01:13:52] minutes or 20 minutes or so, so And
[01:13:54] their liver then makes more ketones for
[01:13:56] the next 12 hours. That's the part that
[01:13:58] I I especially for my cancer patients or
[01:14:00] people who are really I mean, we need
[01:14:03] ketones high for their They got chemo
[01:14:05] tomorrow, they can't afford to say go
[01:14:07] fast for $40, they don't have the time.
[01:14:08] So, let me help you and there's nothing
[01:14:11] better than going into that
[01:14:13] chemotherapy, going into that radiation
[01:14:15] with a bunch of antioxidants in
[01:14:17] circulation coming right out of your
[01:14:18] liver. Explain why that matters. I mean,
[01:14:20] I've got a photo here of a
[01:14:23] Grandma Rose. Grandma Rose. Yeah, that's
[01:14:26] my mother.
[01:14:27] Yes.
[01:14:29] She is the reason I'm here.
[01:14:33] Been 5 years.
[01:14:35] Yeah, 2015. The the most stubborn
[01:14:37] patient
[01:14:39] walks through the door after 10 years of
[01:14:42] the best health care I know how to give.
[01:14:46] And she's gray, she looks like a zombie.
[01:14:50] And she's got big lymph nodes in her
[01:14:51] neck.
[01:14:52] You don't need to be a doctor to know
[01:14:54] that
[01:14:56] she's dying.
[01:14:58] Cancer was back again.
[01:15:01] And we go to see the oncologist and he
[01:15:04] says you need chemotherapy and she says,
[01:15:07] "Like hell. The last two times you did
[01:15:09] that to me, I didn't know what a sewing
[01:15:10] machine was."
[01:15:12] And she made all of my clothes until I
[01:15:14] was the age of 10.
[01:15:18] And she's nervous because she has 6
[01:15:20] months to live we don't do something.
[01:15:23] And she asks me a question that
[01:15:28] lots of patients have asked me this
[01:15:29] question and I just sometimes lie.
[01:15:34] She said, "If it was you, what would you
[01:15:36] do?"
[01:15:38] That's a really emotional question
[01:15:39] because there's guidelines, there's the
[01:15:41] rules, here's what you're supposed to do
[01:15:43] as the doctor.
[01:15:46] But when it's your mom.
[01:15:50] And I have I saw what chemotherapy did
[01:15:52] to her. It was terrible.
[01:15:54] She didn't know
[01:15:56] the grandkids. She didn't It was
[01:15:57] terrible. And we just got her back to
[01:15:59] functional again.
[01:16:03] And so I said I had been reading about
[01:16:05] the ketogenic diet on brain injuries and
[01:16:08] I'd come across a couple of studies on
[01:16:11] what it can do to a cancer patient,
[01:16:12] especially an insulin-driven cancer
[01:16:14] patient like she was.
[01:16:16] I said, "Mom, do you trust me?"
[01:16:20] I'm like, "A fool."
[01:16:23] She said, "With my whole life."
[01:16:28] We were standing there in the in the
[01:16:29] waiting room of the hospital. One way
[01:16:31] was to schedule the chemotherapy and the
[01:16:32] other way was the front door.
[01:16:36] I said, "Mom, let's get in the car
[01:16:37] together."
[01:16:38] I left my car there. I I to my family
[01:16:40] farm, which was 100 miles away.
[01:16:43] And I explained to my mother what a
[01:16:44] ketone was.
[01:16:46] And her brain wasn't working right, so
[01:16:47] she didn't quite remember.
[01:16:49] And we went to the house, we threw out
[01:16:51] every carbohydrate, and man, at 6 weeks
[01:16:55] with chemotherapy, her numbers were
[01:16:57] supposed to drop by 30% of her cancer.
[01:17:00] We didn't tell the doctor, we just put
[01:17:01] her on a ketogenic diet and said,
[01:17:03] "We'll come back in 6 weeks."
[01:17:05] And so she's walking through the door of
[01:17:06] the hospital at 6 weeks from there, and
[01:17:08] it is like God has
[01:17:13] uh
[01:17:14] just the Holy Spirit is rising out of
[01:17:16] her. She looks amazing.
[01:17:21] So we go to get her blood drawn. We're
[01:17:23] sitting in the waiting room for the for
[01:17:24] the cancer doctor.
[01:17:26] And he's my friend. He knows He's known
[01:17:28] me for 10 years, so
[01:17:29] I'm scared to tell him what we're about
[01:17:31] to do.
[01:17:33] So we're sitting in there waiting, and
[01:17:34] they come and draw her blood again,
[01:17:35] which either means it's really good or
[01:17:37] it's really bad.
[01:17:40] And so I get really nervous at the end.
[01:17:41] We've been in that room for about an
[01:17:42] hour, and I said, "Mom, if he asks you
[01:17:44] what you're doing,
[01:17:46] just shut up, cuz I don't know what to
[01:17:47] tell him."
[01:17:50] And he walks in,
[01:17:52] and he slides the piece of paper over to
[01:17:53] me and says,
[01:17:55] "How did you get her numbers to drop by
[01:17:57] 70%? There's no drug on the market that
[01:17:59] would do that."
[01:18:01] When you say numbers? Her cancer
[01:18:03] numbers. So the chemo would have dropped
[01:18:05] it by 30%, and the ketogenic diet
[01:18:07] dropped it by 70% in 6 weeks.
[01:18:12] And she went from a 70-year-old that
[01:18:14] looked 100
[01:18:17] to a 75-year-old who looked 40.
[01:18:22] How did your your mother get on from
[01:18:23] that point onwards? Yeah, she she lived
[01:18:25] her best life. I mean, I talk about her
[01:18:27] being from this little town of 800
[01:18:29] people, she was Mary Poppins. I mean,
[01:18:31] like
[01:18:32] you don't have a ladies aid unless
[01:18:35] you're a part of the ladies aid in the
[01:18:37] in the little small town, you don't have
[01:18:39] a Sunday school teacher unless you're
[01:18:41] doing the Sunday school. She was in
[01:18:43] every aspect of this little town.
[01:18:46] And she went back to doing all of it.
[01:18:49] And the pandemic hit and
[01:18:53] there's a thrift store
[01:18:55] that she would volunteer at because
[01:18:57] well, it's just a good place to put your
[01:18:58] time.
[01:18:59] And the community needs it.
[01:19:01] And while she was at the thrift store
[01:19:04] she got COVID.
[01:19:07] And her cancer was of the T-cells, which
[01:19:09] means it's going to be the first line of
[01:19:11] defense against COVID.
[01:19:14] And her
[01:19:15] her T-cells failed.
[01:19:17] Some of Some of the science behind this
[01:19:19] talks about how cancer cells often rely
[01:19:21] heavily on glucose for energy. A
[01:19:23] phenomenon known as the Warburg effect.
[01:19:25] The keto diet drastically reduces
[01:19:27] carbohydrate intake forcing the body to
[01:19:29] produce ketones for fuel instead of
[01:19:30] glucose. Healthy cells can use ketones
[01:19:32] efficiently. Many cancer cells cannot.
[01:19:33] So, in theory, keto could starve tumors
[01:19:36] while supporting normal tissue. And
[01:19:39] they've done some animal studies that
[01:19:40] show it can slow tumor growth in some
[01:19:43] cancers, especially brain cancers like
[01:19:45] glioblastoma
[01:19:46] >> Glioblastoma, yeah. enhance response to
[01:19:48] radiation or chemotherapy in certain
[01:19:50] models and reduce inflammation and
[01:19:51] oxidative stress creating less a less
[01:19:54] cancer-friendly environment. However,
[01:19:56] results are mixed. They may also benefit
[01:19:59] muscle mass and weight stability in
[01:20:01] patients losing muscle from treatment,
[01:20:02] may improve energy levels and mental
[01:20:04] clarity for some people and could reduce
[01:20:06] insulin and IGF-1 levels, hormones
[01:20:08] linked to cancer growth, may improve
[01:20:09] quality of life when used alongside
[01:20:11] standard treatments like
[01:20:13] chemotherapy. And there's also also a
[01:20:15] list of potential risks which I'll throw
[01:20:17] up on the screen. And I guess the
[01:20:18] summary here is keto may help by
[01:20:19] lowering glucose and insulin, reducing
[01:20:21] inflammation, and supporting that
[01:20:22] metabolism. But it can be risky if it
[01:20:24] leads to malnutrition, fatigue, or worse
[01:20:26] in treatment tolerance. One patient I
[01:20:28] got a lot of people calling and saying,
[01:20:29] "Is it going to help my cancer? Is it
[01:20:30] going to help my cancer?"
[01:20:32] And Stephen, I go back to the same
[01:20:33] thing. The amount of trash that you've
[01:20:35] not been taking out, we have to start.
[01:20:38] And when you put them in a ketogenic
[01:20:39] state, I mean, it really helped her
[01:20:41] cancer. It really did that Warburg
[01:20:43] effect. She was a a new human within 3
[01:20:45] weeks.
[01:20:47] But she had a lot of trash to take out.
[01:20:49] This was a year and a half before she
[01:20:50] got to be the best version of herself.
[01:20:52] And it really did return and restore her
[01:20:55] to to health. When I look at patients
[01:20:57] now who say, you know, can is I am I
[01:20:59] going to reverse my cancer with a
[01:21:00] ketogenic diet? I'm like, no, but you
[01:21:02] are going to deal with it a lot better.
[01:21:04] I guess that's really what it comes down
[01:21:05] to. It's like creating a better
[01:21:06] environment. So that if disease does
[01:21:08] arrive, obviously there is a, you know,
[01:21:10] with a lot of diseases there is a causal
[01:21:13] element where the way we and our
[01:21:14] lifestyle does create the disease.
[01:21:16] Right. Um but also when that disease
[01:21:19] arrives, what like environment is your
[01:21:21] body in to deal with it?
[01:21:22] >> Amen.
[01:21:23] I think a lot about this. I think in
[01:21:24] part because of the pandemic where for
[01:21:26] the first time in my fairly young life,
[01:21:28] I saw that your current
[01:21:31] physiological environment, so your
[01:21:32] current the current state of your body,
[01:21:34] was the single biggest predictor of your
[01:21:35] outcomes.
[01:21:36] >> Amen. Oh, it was terrible. So I was like
[01:21:38] 30 years old and I was like, well, if
[01:21:39] you're currently overweight, your cha-
[01:21:41] chance of
[01:21:42] dying from COVID is really, really high.
[01:21:45] And so I think that was one of the big
[01:21:47] sort of protagonists in me getting into
[01:21:49] shape was realizing that, you know,
[01:21:50] disease is probably going to happen to
[01:21:51] me.
[01:21:52] But how my body responds to it is to be
[01:21:54] determined. Well, and I look at how much
[01:21:57] when you're asking an older person to
[01:21:58] lose weight. And you just read something
[01:22:01] really important there, which is when
[01:22:02] those ketones are in circulation, it is
[01:22:04] a signaling agent to make more ketones,
[01:22:06] but it also signals the body to say
[01:22:08] don't use muscle mass as a resource. Go
[01:22:11] for the fat. So you can see this
[01:22:13] protective I mean, you take people
[01:22:15] through chemotherapy and they have, you
[01:22:17] know, they shed way too many pounds,
[01:22:19] right?
[01:22:20] You put them in a ketogenic state and
[01:22:22] their muscle mass gets higher preserved,
[01:22:23] their brain function, their ability to
[01:22:26] handle this, you know, one of life's
[01:22:28] most enormous fears is death.
[01:22:31] And that
[01:22:32] mood stability and muscle mass
[01:22:34] protection, because they've got ketones
[01:22:36] in circulation, boy, that's the gift
[01:22:38] that they need right now in in high
[01:22:42] numbers. What is um I've heard you talk
[01:22:44] about methylene blue? Oh.
[01:22:46] >> For brain health. Ever done that? No. Oh
[01:22:48] my goodness.
[01:22:48] >> What is it? Well, it's old as dirt.
[01:22:52] So, nobody's making money on it. But it
[01:22:54] is a dye.
[01:22:56] And so, if you swallow it, you'll pee
[01:22:58] blue. But it's also a bridge for how to
[01:23:01] help
[01:23:03] mitochondria move fuel along. So,
[01:23:07] one of the worst parts, you asked me
[01:23:08] this question about supplements. And I
[01:23:10] really have a tough time saying which
[01:23:12] supplements actually get to the cells
[01:23:14] that the patients are looking for.
[01:23:16] There is a really great fact about
[01:23:17] methylene blue that when you swallow it,
[01:23:20] it actually was used for malaria
[01:23:22] treatment or anti-malaria for soldiers.
[01:23:25] And they would check compliance by
[01:23:28] making sure that their pee was blue.
[01:23:31] But when they died, at autopsy, they had
[01:23:33] blue brains and blue hearts.
[01:23:35] It would dye these organs blue. You say,
[01:23:39] "My gosh, that's so strange." But do you
[01:23:41] know what that tells me?
[01:23:42] It got to the cells that it was
[01:23:44] advertising it was going to get to.
[01:23:46] So, you look at methylene blue, it's
[01:23:47] supposed to supercharge your brain. And
[01:23:49] I'm like, "Yeah, yeah, yeah, I've heard
[01:23:50] this before." So, I've I read about it,
[01:23:53] and I'm like, "Wow, there is a lot of
[01:23:54] literature on this." And then I did what
[01:23:57] I normally do, which is, "Well, let me
[01:23:58] take it for a couple weeks." It was
[01:24:00] amazing. It was amazing. Like
[01:24:04] I I was floored at how well that little
[01:24:06] trick you worked. So, there's no money
[01:24:08] to be made on it. It's a It's been
[01:24:09] around as long as dirt. But
[01:24:12] it's a powerful brain energizer. Like it
[01:24:15] helps the mitoch- the electrical
[01:24:17] stimulus of the mitochondria in your
[01:24:19] brain keep energy high.
[01:24:21] Especially for like high energy brains,
[01:24:24] I I love it. I'm like I put that in my
[01:24:27] morning morning coffee.
[01:24:29] Which is where I the April Fool's joke,
[01:24:31] because nobody can see it in their
[01:24:32] coffee, but they definitely pee blue.
[01:24:34] And do you take creatine as well? I do
[01:24:36] take creatine, yeah. Yeah, it's great.
[01:24:37] That brain supplement is awesome. Do you
[01:24:39] do? I do, but I might talk to the other
[01:24:40] day, I think he was suggesting that I
[01:24:42] might have taken too much. Why? Some
[01:24:44] liver scan I had and he was saying that
[01:24:46] Liver scan or kidney scan?
[01:24:48] >> Kidney scan, that was Kidney scan. So,
[01:24:49] that's a trick. Don't don't fall for
[01:24:51] that. I mean, I've done a couple of big
[01:24:53] shows on this where creatine is what
[01:24:55] you're going to measure kidney function
[01:24:56] with. You know, when your doctor checked
[01:24:58] your kidneys, he probably had you pee in
[01:24:59] a cup and check your blood. Yeah. Yeah,
[01:25:01] so he's looking at what did you pee out
[01:25:02] and what how clean is your blood? That's
[01:25:04] what kidneys do. He just did a blood
[01:25:05] test. Okay, well, even the blood test,
[01:25:07] it the trash was looking like it was a
[01:25:09] little higher
[01:25:10] because the trash you're measuring is
[01:25:12] creatine.
[01:25:13] Uh creatinine, uh and which is made from
[01:25:16] your supplement. So, you put the
[01:25:18] supplement in and it looks like there's
[01:25:19] more trash around, but
[01:25:21] that's just the supplement. It's falsely
[01:25:23] elevated. It's not true. You your
[01:25:25] kidneys did not get hurt by that. This I
[01:25:27] answer this question probably 30 times a
[01:25:28] week. I have a standard email saying,
[01:25:30] "Here's what happened. Don't measure
[01:25:32] that." There's other ways you could have
[01:25:33] measured your kidney that would not have
[01:25:35] been manipulated by that supplement. Uh
[01:25:38] what it does for brain function,
[01:25:39] especially if there's any ADHD, man,
[01:25:41] they love it. They they just focus for a
[01:25:44] long period of time. I mean, it's got
[01:25:45] other great findings like if you how how
[01:25:49] often do you fly over to London?
[01:25:51] I fly a lot. Yeah, that's the best part
[01:25:53] about it is that the the the jet lag
[01:25:55] part of it is really good studies on
[01:25:57] this. Like, your reset of sleep is going
[01:26:00] to be augmented if you take like 20 g of
[01:26:04] it after the flight.
[01:26:06] 10 in the morning, 10 at night. Uh and
[01:26:08] those are great studies. Like, you know,
[01:26:10] Navy SEALs
[01:26:11] just sleep deprived, watch what happens
[01:26:14] when you add creatine.
[01:26:15] A lot of women don't take creatine cuz
[01:26:16] they've historically thought of it as
[01:26:18] like a bodybuilder thing.
[01:26:19] >> Right. It's a brain thing. And you take
[01:26:21] creatine every day. Mhm. How much do you
[01:26:22] take? So, two scoops.
[01:26:24] Yeah.
[01:26:25] >> Every single day.
[01:26:25] >> Every single day.
[01:26:26] >> 7 days a week.
[01:26:26] >> I put my methylene blue in it, too. Down
[01:26:29] it first thing in the morning. I got
[01:26:30] blue-dyed creatine.
[01:26:33] I mean, those two supplements are just
[01:26:34] they they blew my mind with the amount
[01:26:35] of research out there, and then I did
[01:26:37] them.
[01:26:38] Uh I mean, I'm not a big bodybuilder. I
[01:26:39] do some crossfitty kind of stuff three
[01:26:41] times a week.
[01:26:43] Um so, there's that, but I do it for the
[01:26:45] brain The brain stuff is really
[01:26:47] impressive.
[01:26:48] At the moment in society, people are
[01:26:50] talking a lot about
[01:26:51] GLP-1s and Ozempic and all this kind of
[01:26:53] stuff. And um I was wondering if there's
[01:26:56] any
[01:26:57] harms or downsides in your view of using
[01:26:59] these Ozempic, Wegovy, GLP-1
[01:27:03] protagonists. Antagonists, yeah.
[01:27:05] Antagonists.
[01:27:05] >> Antagonists, antagonists. Antagonists.
[01:27:07] And if there's a natural version
[01:27:09] for those of us that are looking to have
[01:27:12] less cravings.
[01:27:14] Um but but we don't want to take GLP-1s.
[01:27:16] We don't want to be injecting ourselves.
[01:27:17] Yeah, so those hormones are powerful. I
[01:27:19] mean, you if you think that weight loss
[01:27:21] isn't a hormonal problem,
[01:27:22] uh
[01:27:23] show up at a medical clinic. That That
[01:27:26] they are powerful hormones that hijack
[01:27:29] people into a healthier
[01:27:32] uh or at least a weight loss stage. But
[01:27:34] when you're looking at using this
[01:27:36] powerful hormone, okay, and use it for a
[01:27:38] short time, use it for a long time, what
[01:27:40] are the rules? These are brand new.
[01:27:42] One of the analogies I use for patients
[01:27:43] is
[01:27:44] Steven, if you wanted to have legs with
[01:27:46] no hair on them, how would you
[01:27:48] accomplish that?
[01:27:49] >> Shave them. Right, because that would be
[01:27:51] short-term, easy, and reversible. You
[01:27:53] would not take
[01:27:54] chemotherapy, the most powerful,
[01:27:57] amazing, they'll be every hair on your
[01:27:59] body will be off in the next 2 weeks.
[01:28:02] And it's short-term, they'll come back,
[01:28:04] but there's a price to pay when you're
[01:28:05] using a really powerful unit to do
[01:28:07] something for a vanity reason.
[01:28:10] So, it's where I like to begin when I
[01:28:12] talk about GLP-1s.
[01:28:14] It's It's amazing. You will lose fat and
[01:28:17] So, what do I do instead then?
[01:28:19] So, there's great ways to lower
[01:28:22] GLP-1s or great ways to raise GLP-1s,
[01:28:24] right? Uh for starters,
[01:28:27] um
[01:28:28] when you're overweight, it suppresses it
[01:28:30] a lot. So, getting the weight off is a
[01:28:31] huge part of it. That's why this
[01:28:32] ketogenic diet is so powerful. We'll get
[01:28:34] the weight off. And that will lift
[01:28:36] naturally the GLP-1s. Is there other
[01:28:38] ways to suppress um well, suppress to I
[01:28:42] was going to say suppress my appetite,
[01:28:43] but more to just get rid of the
[01:28:44] cravings.
[01:28:45] >> Well, you'll suppress the appetite by
[01:28:47] raising those hormones. So, you put in
[01:28:48] allulose, that's a great little boost to
[01:28:50] that. You put in
[01:28:52] butyrate. Whether or not that's the bug
[01:28:54] that you were talking about or
[01:28:56] the supplements.
[01:28:58] Butyrate increases and stimulates GLP-1.
[01:29:01] And butyrate
[01:29:03] just for for those that might not know
[01:29:04] that word again. Right. That's a That is
[01:29:06] what a ketone looks like floating around
[01:29:07] your blood. Okay. Yeah.
[01:29:09] Uh so, a ketogenic state will raise
[01:29:11] those hormones and suppress appetite.
[01:29:13] I've seen a bunch of studies on that
[01:29:14] that show that when people are high in
[01:29:16] ketones
[01:29:17] >> ketones, they have a a suppressed
[01:29:18] appetite.
[01:29:19] >> Right. And that is linked to the
[01:29:20] production of some of these hormones,
[01:29:21] these really great hormones. But, you
[01:29:23] make them naturally, and so it's not the
[01:29:25] addiction part. It's the natural way to
[01:29:27] make it.
[01:29:27] >> I I do find that anyway. I find that
[01:29:28] when I'm
[01:29:30] I guess it could be something to do with
[01:29:31] my dopamine receptors as well in my
[01:29:32] brain, but I find that when I'm in a
[01:29:33] ketogenic diet, my cravings for the
[01:29:34] things that I once craved, like I don't
[01:29:37] know, like carrot cake or cinnamon
[01:29:39] rolls,
[01:29:40] they just completely seem to vanish.
[01:29:42] That's the same thing that happens when
[01:29:43] you give them that shot, too.
[01:29:45] Oh, really? When you give them GLP-1?
[01:29:46] Yes. Okay. And I mean, the beautiful
[01:29:48] part is
[01:29:49] you're young. You'll make a lot of GLP-
[01:29:51] You've already made healthy GLP-1.
[01:29:53] You'll hijack and suppress it by being
[01:29:55] overweight and high insulin.
[01:29:57] So, constantly delivering ketones to
[01:29:59] your blood, that's how you keep it high.
[01:30:01] Then you don't end up on the shot, which
[01:30:03] is expensive
[01:30:04] and very powerful. I always think, you
[01:30:06] know, when we give people advice on
[01:30:08] things like weight loss,
[01:30:09] there's always a part missing, which is
[01:30:11] this part about like discipline and
[01:30:12] motivation or whatever one might call
[01:30:14] it, which is the
[01:30:16] is gives somebody the sort of activation
[01:30:18] energy to even stick to it. Do you think
[01:30:21] about this much in your patients? Do you
[01:30:23] think about motivation? It's huge. I
[01:30:24] mean, again, most people show up because
[01:30:26] there's been a recent crisis. Somebody
[01:30:28] died, they had a diagnosis, something
[01:30:30] broke, they didn't repair well. All of
[01:30:32] that is true, and I can get them
[01:30:33] motivated for a little while.
[01:30:36] And then we have the long game. You look
[01:30:37] at that story with 100 days of sardines,
[01:30:40] okay? That's 2 years into her journey,
[01:30:42] where she finally says, "Okay, there's
[01:30:43] this demon that keeps coming about, and
[01:30:45] I keep falling off for all the wrong you
[01:30:47] know, all the reasons everybody else
[01:30:48] does."
[01:30:49] And so she commits to this 100 days. And
[01:30:51] what happens is a whole bunch of things
[01:30:53] go right, her hormones go up,
[01:30:55] and she has an amazing story. But most
[01:30:58] people are not going to do that.
[01:31:00] So, in my practice, I do say these
[01:31:03] the smallest dose of these hormones,
[01:31:05] I'll help you when you're struggling. I
[01:31:07] want you in a ketogenic state before we
[01:31:09] we begin. I can use much less of that
[01:31:11] hormone, and then you have ownership of
[01:31:13] this. Because if I come in and do all of
[01:31:16] the work again,
[01:31:17] it's like every other thing I've been
[01:31:19] doing for the last 20 years. Here's your
[01:31:20] symptom, here's my diagnosis, here's the
[01:31:22] prescription.
[01:31:24] And I need it to be you that succeeds
[01:31:26] here.
[01:31:27] I'll lift you a little bit. So, what do
[01:31:28] you Is there any tricks to get someone
[01:31:30] to be motivated? Is there any Do you
[01:31:32] have to focus them on their why?
[01:31:33] >> Yeah. Exactly, right. You're right. Uh
[01:31:35] that that first trick is get out of
[01:31:37] crisis mode, okay? The crisis is what
[01:31:40] brings them in, but to stay the course,
[01:31:43] you have to get to a very serious moment
[01:31:44] where you say, "What What motivates me?
[01:31:48] What at the deepest heart am I most
[01:31:49] insecure about that I am going to do
[01:31:51] when all else fails? When everybody else
[01:31:54] gives up?
[01:31:55] I'm going to find something that I'm
[01:31:57] this little farm kid from the middle of
[01:31:59] nowhere, who was you know, third grade
[01:32:01] stinky girl. You know, like I was a farm
[01:32:03] kid. I was a hog farmer's daughter. I
[01:32:05] wasn't the smart one. I wasn't the, you
[01:32:07] know, the best one. I'm going to carry
[01:32:09] that insecurity with me until the day I
[01:32:11] die. What has that done? It makes me
[01:32:13] work really hard when everybody else
[01:32:15] gives up.
[01:32:16] Now, finding that for them
[01:32:20] and and using that using that harness to
[01:32:22] say, "Your biggest failure, your biggest
[01:32:25] insecurity can be your power
[01:32:27] by reframing it."
[01:32:30] And that why we work on that every time
[01:32:32] we do that 21-day.
[01:32:34] Jane, she did that four times before she
[01:32:36] really got to the core center. Why do
[01:32:38] you keep doing this?
[01:32:41] That's how people stay motivated. It's a
[01:32:43] true It's a truth serum.
[01:32:46] All I had to do was brain dump. Imagine
[01:32:48] if you had someone with you all times
[01:32:51] that could take the ideas you have in
[01:32:53] your head, synthesize them with AI to
[01:32:55] make them sound better and more
[01:32:56] grammatically correct, and write them
[01:32:58] down for you. This is exactly what
[01:33:00] WhisperFlow is in my life. It is this
[01:33:02] thought partner that helps me explain
[01:33:04] what I want to say, and it now means
[01:33:06] that on the go, when I'm alone in my
[01:33:08] office, when I'm out and about, I can
[01:33:10] respond to emails and Slack messages and
[01:33:12] WhatsApps and everything across all of
[01:33:14] my devices just by speaking. I love this
[01:33:16] tool. And I started talking about this
[01:33:17] in my behind-the-scenes channel a couple
[01:33:19] of months back, and then the founder
[01:33:20] reached out to me and said, "We're
[01:33:21] seeing a lot of people come to our tool
[01:33:23] because of you. So, we'd love to be a
[01:33:24] sponsor. We'd love you to be an investor
[01:33:26] in the company." And so, I signed up for
[01:33:27] both of those offers, and I'm now an
[01:33:28] investor and a huge partner in a company
[01:33:31] called WhisperFlow. You have to check it
[01:33:33] out. WhisperFlow is four times faster
[01:33:35] than typing. So, if you want to give it
[01:33:37] a try, head over to whisperflow.ai/doac
[01:33:40] to get started for free. And you can
[01:33:42] find that link to WhisperFlow in the
[01:33:44] description below.
[01:33:46] Have you ever heard about this before,
[01:33:48] this thing I'm holding in my hands now?
[01:33:49] This is called KetoneIQ. The website is
[01:33:52] ketone.com. You've heard me on this
[01:33:54] podcast talking about the fact that I
[01:33:55] stay much of the year in a ketogenic
[01:33:57] state, which is a highly restricted
[01:33:59] diet. And the reason I do that is
[01:34:01] plentiful. One of them is I spend hours
[01:34:03] and hours talking to people for a
[01:34:04] living. So, I want to make sure my brain
[01:34:06] is firing in an optimal way. And the
[01:34:08] other reason that I do the ketogenic
[01:34:10] diet is because I just feel better. So,
[01:34:13] when I discovered this, which is what
[01:34:15] they call an exogenous ketone product,
[01:34:17] where you can drink it and it increases
[01:34:19] your blood's ketone levels, I was blown
[01:34:22] away. I contacted them, I met them, I
[01:34:24] invested extremely heavily into their
[01:34:26] company, and I've become a co-owner of
[01:34:28] the company accordingly, and they
[01:34:29] sponsor this show now. So, if you want
[01:34:31] to try this out for yourself,
[01:34:33] I recommend you try it. Just visit
[01:34:35] ketone.com/steven
[01:34:37] and you'll get 30% off your first
[01:34:39] subscription order. You'll also get a
[01:34:40] free gift with your second shipment.
[01:34:42] That's ketone.com/steven.
[01:34:47] I was reading about what happened to you
[01:34:48] in 2011, 2010, 2011, when you reach what
[01:34:51] you you refer to as your breaking point
[01:34:53] in corporate medicine.
[01:34:55] Yeah.
[01:34:55] >> And you had some issues because you were
[01:34:58] I think helping some people who
[01:35:01] were homeless. Yep. What what do what do
[01:35:04] I need to know about that and how has
[01:35:06] that shaped you? Corporate medicine has
[01:35:08] lots of flaws, and you get tired of
[01:35:11] answering the same question over and
[01:35:12] over and over again.
[01:35:13] So, you put some stuff up on YouTube and
[01:35:15] you start to say, "Here's the education
[01:35:17] I wish I could give you."
[01:35:19] Uh and this starts to work.
[01:35:21] But that's not the that's not the path
[01:35:23] if you're in a corporate medicine.
[01:35:24] You're going to ruffle feathers, you're
[01:35:25] going to tick people off.
[01:35:27] I left corporate medicine, started my
[01:35:29] own thing, and I'm living out a 2-year
[01:35:32] non-compete.
[01:35:34] Do you know what that means?
[01:35:35] That you can't do medicine for 2 years?
[01:35:38] In that same market where they recruited
[01:35:40] me and they had advertised for me. Okay.
[01:35:42] Okay? So, you can't compete with what we
[01:35:44] just put money into for 2 years. And
[01:35:47] they said, "You can see the homeless and
[01:35:49] you can see Medicaid." Medicaid being
[01:35:51] the like government-funded medical
[01:35:52] medicine program.
[01:35:53] >> Low income. So, I said they don't know
[01:35:55] me very well. Those are just as much my
[01:35:56] people as anybody else.
[01:35:58] I'm taking care of some Native
[01:35:59] Americans. They were the ones in the
[01:36:00] shelters. They're the ones with the low
[01:36:02] income.
[01:36:03] And
[01:36:05] those teenagers were overweight and they
[01:36:07] were eating kitty litter.
[01:36:09] They were eating toilet paper.
[01:36:11] Their iron was
[01:36:13] so low the machine couldn't measure it.
[01:36:15] So, they're super malnourished.
[01:36:17] I started doing what I would do if you
[01:36:18] had all the money in the world. I took
[01:36:20] care of these patients.
[01:36:21] I gave them IV iron. She gave them iron.
[01:36:24] Which was expensive. It caused a ruckus.
[01:36:26] I got put on the radar of somebody that
[01:36:28] did not like that.
[01:36:30] So, this is the budget. The whole state
[01:36:31] gets a budget for how much you're going
[01:36:33] to spend on each patient. Yeah. I mean
[01:36:35] by expensive it was like 350 bucks per
[01:36:37] person. That's not that expensive.
[01:36:38] >> Mhm. But it was and nobody else was
[01:36:40] doing it.
[01:36:42] And I got a sticky note inside an
[01:36:44] envelope from the state capital. Stop
[01:36:46] doing Cadillac medicine.
[01:36:49] Yeah. So, you you were sued eventually?
[01:36:52] Oh, they they called Medicaid fraud.
[01:36:54] Okay. They thought I was wasting
[01:36:56] Medicare's numbers because I was giving
[01:36:58] IV iron. And I said, "No, I didn't bill
[01:37:00] for it bill for it. I paid for it."
[01:37:03] And when I paid for the medicine for
[01:37:05] these
[01:37:06] impoverished patients, they said, "Well,
[01:37:08] that's Medicaid fraud."
[01:37:10] So, the government tried to sue me for
[01:37:12] that and they lost. But now they're
[01:37:13] ticked off.
[01:37:15] They've brought me to court and they
[01:37:16] lost.
[01:37:17] And
[01:37:19] what happened next is a lot worse.
[01:37:22] I don't know if you want to hear that.
[01:37:22] Do you want me to go there?
[01:37:23] >> Of course, yeah.
[01:37:24] >> Okay.
[01:37:25] So,
[01:37:27] when you are being investigated for
[01:37:29] Medicaid fraud, all income stops.
[01:37:31] Yeah. Yeah. So,
[01:37:34] I have to come home to my husband and
[01:37:35] say,
[01:37:36] "I just can't I can't give in. I think
[01:37:39] we need to fight this."
[01:37:41] He said, "Okay."
[01:37:43] He he he
[01:37:44] God bless him. He I "Okay, let's fight
[01:37:45] it."
[01:37:46] Have you ever tried to fight the
[01:37:47] government?
[01:37:49] It's very expensive. So, they hold off
[01:37:52] when you're under a Medicaid and
[01:37:53] fraud investigation, you get no
[01:37:55] paychecks. So, we have no paychecks to
[01:37:56] pay payroll, to pay house payments, to
[01:37:58] do anything for about 9 and 1/2 months.
[01:38:02] Actually, it lasted longer than that.
[01:38:03] During that time, we started doing
[01:38:05] things like
[01:38:07] we sold the lake cabin, we sold the
[01:38:08] boats, we sold the extra car.
[01:38:11] We sold our own house.
[01:38:12] We moved into a donated RV.
[01:38:15] You moved into a car?
[01:38:17] An RV, yep.
[01:38:19] In South Dakota, where there's 50 below
[01:38:21] zero weather.
[01:38:22] With three little kids.
[01:38:24] We actually
[01:38:26] used
[01:38:27] we took our wedding rings in for the
[01:38:29] last paycheck.
[01:38:31] I I just can't give in.
[01:38:34] And then I won. Okay, so Medicaid fraud
[01:38:36] wasn't there.
[01:38:38] But in the midst of that, I said
[01:38:40] I This is when Obamacare was really
[01:38:42] happening.
[01:38:43] And I got asked to run for US Senate.
[01:38:46] There's only 100 of those in the
[01:38:47] country.
[01:38:49] I run for US Senate and I did really
[01:38:51] good.
[01:38:54] I raised
[01:38:56] insane amounts of money.
[01:38:57] Uh saying, "I am a doctor that serves
[01:39:00] the poor.
[01:39:01] I am a physician that runs her own
[01:39:03] company.
[01:39:04] Uh I think I am a great voice to send to
[01:39:07] Washington DC to make policy about
[01:39:09] patients and care
[01:39:12] as opposed to the other opponents."
[01:39:15] But that same attorney general
[01:39:17] his best buddy was running against me.
[01:39:20] And when I am in a mission trip
[01:39:22] uh in the Philippines that has nothing
[01:39:25] to do with it, but I was on a mission
[01:39:26] trip in the Philippines.
[01:39:27] And um I left a petition behind. I don't
[01:39:31] know how you do it in London, but a
[01:39:32] petition means if you're going to run
[01:39:33] for office, you got to get some people
[01:39:35] saying it they believe in you.
[01:39:37] >> Mhm. So, we needed 2,000 signatures.
[01:39:39] And we got 6,000 signatures. We
[01:39:42] submitted them to the state.
[01:39:44] We think there's no problem.
[01:39:46] But then the quarterly earnings come
[01:39:47] back for a campaign raising and my
[01:39:49] opponent
[01:39:51] had about 70 donors at about $10,000
[01:39:55] a pop and we had something like 740,000
[01:40:00] dollars.
[01:40:01] I put my earnings in and they were
[01:40:03] 780,000 dollars. So I out raised him.
[01:40:07] You have to report to the government
[01:40:09] whenever somebody gives you more than
[01:40:10] 200 dollars.
[01:40:12] So his donors are right there on the
[01:40:13] list.
[01:40:15] My list is empty.
[01:40:18] Because the average size of the donation
[01:40:19] was 45 dollars.
[01:40:21] And they know they can't win with that.
[01:40:24] I have a grassroots behind me.
[01:40:26] And that's when the black cars started
[01:40:29] showing up in my life. It sounds like
[01:40:31] I've got a tin foil hat, but it was
[01:40:32] real.
[01:40:34] The black what? The state card started
[01:40:37] to show up outside my house.
[01:40:39] They started to say, "Find something on
[01:40:41] her."
[01:40:42] And I am the first person in the history
[01:40:45] of the United States of America
[01:40:47] to be investigated for not witnessing a
[01:40:50] signature on those petitions. Okay, so
[01:40:53] there was these petitions you had to get
[01:40:54] 2,000 of them signed and you had to
[01:40:57] witness them. So you had to be there
[01:40:58] when they were signed by people?
[01:41:00] >> Well, that's what it says and you're
[01:41:01] right. It says, "I bear witness." So as
[01:41:05] I'm I left them in my clinic, my staff
[01:41:08] signed it. The preachers in my
[01:41:11] my clinic signed it.
[01:41:13] And those signatures were collected
[01:41:14] while I was in the Philippines. And so
[01:41:17] you signed to witness them when you were
[01:41:18] back from the Philippines.
[01:41:19] >> Right. So I didn't witness them. I just
[01:41:21] vouched that that's my sister, that's
[01:41:24] the preacher. I know who these people
[01:41:25] are. And so they
[01:41:28] charged you for they realized that you
[01:41:30] were in the Philippines at the time so
[01:41:31] you couldn't have witnessed them based
[01:41:32] on the dates or something. Yep. And then
[01:41:34] they arrested you? I 12 12 felonies.
[01:41:38] They give you 12 felonies? And 24 years
[01:41:40] in prison.
[01:41:43] That's what they charged you for or
[01:41:45] that's what They charged me the 12
[01:41:47] felonies. Six counts for each of the six
[01:41:49] petitions. Six uh so that's 12 felonies.
[01:41:52] There's six mistakes, but each mistake
[01:41:54] counts for two felonies. I mean, if
[01:41:56] you're going to make a mistake, there's
[01:41:58] one felony. Mhm. When you're trying to
[01:42:01] make a statement,
[01:42:03] there's 12 felonies.
[01:42:05] And you're the first one in the history
[01:42:06] of the United States of America to ever
[01:42:08] have this charge, let alone brought to
[01:42:10] trial.
[01:42:12] And then found guilty.
[01:42:14] The trial didn't happen in my state, my
[01:42:16] town. It happened in
[01:42:18] the state capital,
[01:42:20] where everybody knew that attorney
[01:42:22] general, everybody knew the opponent.
[01:42:24] So they they tried to get you to serve
[01:42:26] 24 years in prison? Yeah. They sentenced
[01:42:28] me to 24 years in prison. They sentenced
[01:42:30] you to
[01:42:30] >> Yeah.
[01:42:31] My kids were sitting behind me. I'm you
[01:42:33] are guilty of 12 felonies and 24 years
[01:42:36] in prison.
[01:42:38] And then he says, "But this stack of
[01:42:39] papers in front of me
[01:42:41] might be the biggest he'd been a judge
[01:42:43] for 20-some years.
[01:42:45] And I had patients who had written in
[01:42:46] saying, "This is the best doctor I've
[01:42:48] ever seen."
[01:42:49] I didn't ask them to write that. They
[01:42:50] just sent them in. How did you feel when
[01:42:52] you hear that you're going to be in
[01:42:53] prison for 24 months? 24 years?
[01:42:56] Oh god, it is the lowest moment of my
[01:42:58] life.
[01:43:00] Because
[01:43:01] I mean, I do not like that the that that
[01:43:04] story cost the state of South Dakota any
[01:43:06] money.
[01:43:08] But I also don't like that when you
[01:43:10] oppose
[01:43:11] the the political giants,
[01:43:16] and you stand there with all of the
[01:43:18] right intentions,
[01:43:19] that if they need to find something on
[01:43:21] you, they will.
[01:43:24] Six petitions.
[01:43:26] And we had a thousand extra signatures.
[01:43:30] There was noth- This was a
[01:43:31] nothingburger. but it was enough and
[01:43:34] that attorney general said
[01:43:37] prosecute her to the fullest extent.
[01:43:40] And I'm not a martyr. I do things that
[01:43:42] aren't right and if there was a mistake
[01:43:44] that I made, I I would take full
[01:43:46] ownership and to that judge I made I
[01:43:48] took full ownership.
[01:43:50] That the attorney general was he won.
[01:43:55] I got sentenced.
[01:43:57] But you didn't have to serve the 24
[01:43:58] years. He said I'll probate that. I will
[01:44:01] suspend that with
[01:44:03] the highest number of service hours ever
[01:44:05] in the state of South Dakota. It was 500
[01:44:08] community service hours serving the
[01:44:10] poorest patients in the state. And when
[01:44:11] he said those words I thought, "Oh my
[01:44:13] god, you don't know who I am."
[01:44:15] That's what I've been doing. I was
[01:44:16] already working in Pine Ridge.
[01:44:18] How did you How did you feel about all
[01:44:20] of this? I mean I I think of it as a
[01:44:21] test.
[01:44:23] It was a test of
[01:44:25] I mean most marriages aren't going to
[01:44:26] make it through that.
[01:44:28] You got kids that'll end up in rehab at
[01:44:30] that much stress.
[01:44:31] And I didn't want that life. I didn't
[01:44:34] want that to be my
[01:44:37] ending.
[01:44:38] I framed it different. I said, "All
[01:44:39] right, God, you're testing me.
[01:44:42] You're testing to see can I be Can I
[01:44:44] stay true to who it is that you've
[01:44:46] called me to be?"
[01:44:49] That
[01:44:51] our marriage was incredibly
[01:44:54] That's a lot of pressure. I mean, I was
[01:44:55] the number one news story in the whole
[01:44:57] damn state for 3 years running by a
[01:44:59] mile.
[01:45:01] I can't go anywhere without
[01:45:03] That's her. That's her. My parents were
[01:45:05] ashamed.
[01:45:07] My kids would say, "This is the woman
[01:45:08] that takes me to Haiti. She is Mother
[01:45:11] freaking Teresa and now she's on the
[01:45:13] front page of a newspaper as a 12-time
[01:45:15] felon."
[01:45:16] And your teachers at school say
[01:45:20] I read about your mom again in the
[01:45:21] newspaper.
[01:45:22] I mean, it's a old
[01:45:24] It should have crushed me.
[01:45:29] But it didn't. It did not.
[01:45:31] When did your life begin to turn upwards
[01:45:33] from that point onwards? When was the
[01:45:35] the moment where
[01:45:37] things were
[01:45:39] Well, the first thing is we appealed
[01:45:40] that to the Supreme Court. Yeah.
[01:45:42] >> That's where the big legal bills come
[01:45:43] from.
[01:45:44] Second, you're fighting an attorney
[01:45:45] general. That's where all
[01:45:47] And the Supreme Court said that that
[01:45:49] attorney general abused his power
[01:45:51] for at least six of them.
[01:45:52] And then that judge said
[01:45:54] I'll erase all these because of the work
[01:45:56] you've done. So, the 12 felonies went
[01:45:58] away
[01:45:59] during
[01:45:59] >> them? All of them.
[01:46:01] I think on the edge of that story, um
[01:46:04] I work to resurrect people's health back
[01:46:06] to a place where they they get their
[01:46:08] best life.
[01:46:10] And yes, ketones are really a big part
[01:46:11] of that.
[01:46:13] But as you look at the relationships
[01:46:16] you've got around your life
[01:46:18] take the core ones and nurture them to a
[01:46:20] place where
[01:46:22] uh
[01:46:22] your best life comes out of those
[01:46:23] relationships.
[01:46:25] Find the purpose that you've been
[01:46:26] designed for.
[01:46:28] And take those relationship with you as
[01:46:30] you seek that.
[01:46:32] I know that's what happened to me.
[01:46:35] I cared about the ones on the inner
[01:46:36] circle and I had a one track of this is
[01:46:38] what I'm designed to do.
[01:46:41] We have a closing tradition where the
[01:46:42] last guest leaves a question for the
[01:46:43] next. And the question left for you is,
[01:46:45] do you have a daily practice
[01:46:48] to find deep inner peace when you are
[01:46:51] emotionally triggered? And if so, please
[01:46:55] share it with the audience.
[01:46:58] Yeah, I have a uh devotion that I do
[01:47:00] every morning.
[01:47:01] That um
[01:47:03] that centers me, keeps me
[01:47:05] in line with my faith.
[01:47:08] And that's not that you do it on the bad
[01:47:10] days. It's that you've got the
[01:47:12] foundation for doing it on the good
[01:47:13] days. And there are
[01:47:16] generations
[01:47:17] >> Uh
[01:47:17] the a daily devotion. Like Upper Room is
[01:47:20] a is a spiritual devotion for
[01:47:23] my church. What what does that look
[01:47:24] like? Is it a prayer or Yeah, it's a
[01:47:26] prayer. And
[01:47:27] >> And how does that sound? What is
[01:47:29] Yeah, the it's a usually a scripture and
[01:47:30] then it's a prayer that is been
[01:47:33] uh paired with that scripture.
[01:47:36] And again, it's easy to not do it
[01:47:37] routinely.
[01:47:38] But when you practice it on the good
[01:47:40] days,
[01:47:41] it's what lifts you on those really
[01:47:43] tough days.
[01:47:45] And sometimes you forget you're not the
[01:47:46] first person to run through these
[01:47:47] problems.
[01:47:49] But there are
[01:47:50] thousands of generations that have
[01:47:53] taught you how to do life and get
[01:47:55] through those hard places.
[01:47:57] And I'm going to use their rules.
[01:48:00] I'm going to follow what that
[01:48:03] scripture says
[01:48:05] and live for my best life.
[01:48:07] Dr. Bosworth, thank you.
[01:48:09] Very good. We are done. I really think I
[01:48:11] really appreciate so much about you. I
[01:48:13] appreciate your personality.
[01:48:14] Well, I could have been engaging, but
[01:48:16] also just um I appreciate that you've
[01:48:18] taken the time to make so much content
[01:48:20] over on your YouTube channel, which I'm
[01:48:22] going to link on screen and below now
[01:48:24] um to sort of demystify and break down
[01:48:26] some of these really complicated
[01:48:28] subjects that people struggle with and
[01:48:30] they're looking for someone who they can
[01:48:31] trust, who has a bit of personality.
[01:48:33] Um who can communicate some of these
[01:48:36] very complicated things to them. And on
[01:48:37] your channel you talk about everything
[01:48:38] from the ketogenic diet to many of the
[01:48:41] things we talked about today to the
[01:48:42] creatine stuff to cancer more broadly,
[01:48:45] the scientific theory of autophagy and
[01:48:47] fasting um and lots of other things and
[01:48:50] everything we've talked about today and
[01:48:51] much, much, much more. So I highly
[01:48:52] recommend people go and check your
[01:48:53] channel out if they would like to learn
[01:48:55] more. It will be linked below.
[01:48:58] And um you've written some wonderful
[01:48:59] books. Um
[01:49:00] some of them that we've referenced.
[01:49:02] We've got the Keto Continuum, which I'm
[01:49:03] going to link below as well. Um this
[01:49:05] wonderful book called Anyway You Can, a
[01:49:07] Beginner's Guide to Ketones for Life,
[01:49:09] which um talks a lot about Rose and has
[01:49:11] some wonderful photos of Rose in that
[01:49:14] book. And we have the the Continuum
[01:49:15] Workbook, which is a much more practical
[01:49:18] um Yeah, it goes hand in hand with the
[01:49:20] other one and it's what I give my
[01:49:21] patients in the clinic as they got to go
[01:49:24] through that workbook. I think a lot of
[01:49:25] people are looking for exactly that.
[01:49:26] They're looking for something that they
[01:49:28] can follow step by step, which gives
[01:49:30] them a framework for progress and I
[01:49:31] guess in in a way holds them
[01:49:32] accountable, which is exactly what the
[01:49:33] workbook does.
[01:49:35] Thank you so much. You're you're you're
[01:49:36] helping millions of people. You've had a
[01:49:37] [ __ ] rough ride and been outside. 12
[01:49:39] felonies and 24 years in prison is for
[01:49:42] for something as as little as what you
[01:49:43] did, I think is is bizarre.
[01:49:46] Quite frankly, but you know, it's a
[01:49:48] story of inspiration that it didn't hold
[01:49:49] you back and you've risen like a phoenix
[01:49:51] and created so much incredible work
[01:49:53] therefore that's benefit so many. So
[01:49:54] please do keep going.
[01:49:56] God bless you. Thanks for having me
[01:49:57] here. I'm really excited to be on your
[01:49:58] show. Thank you so much, Dr. Boz.
[01:50:03] This is something that I've made for
[01:50:05] you. I realize that the Diary of a CEO
[01:50:07] audience are strivers, whether it's in
[01:50:09] business or health. We all have big
[01:50:11] goals that we want to accomplish. And
[01:50:12] one of the things I've learned is that
[01:50:14] when you aim the big big big goal, it
[01:50:17] can feel incredibly psychologically
[01:50:20] uncomfortable because it's kind of like
[01:50:22] being stood at the foot of Mount Everest
[01:50:23] and looking upwards. The way to
[01:50:25] accomplish your goals is by breaking
[01:50:27] them down into tiny small steps and we
[01:50:30] call this in our team the 1%. And
[01:50:31] actually this philosophy is highly
[01:50:33] responsible for much of our success
[01:50:35] here. So, what we've done so that you at
[01:50:38] home can accomplish any big goal that
[01:50:39] you have is we've made these 1% diaries
[01:50:43] and we released these last year and they
[01:50:44] all sold out. So, I asked my team over
[01:50:47] and over again to bring the diaries back
[01:50:48] but also to introduce some new colors
[01:50:50] and to make some minor tweaks to the
[01:50:51] diary. So now we have a better range for
[01:50:56] you. So, if you have a big goal in mind
[01:50:58] and you need a framework and a process
[01:51:00] and some motivation, then I highly
[01:51:02] recommend you get one of these diaries
[01:51:04] before they all sell out once again. And
[01:51:06] you can get yours now at the diary.com
[01:51:08] where you can get 20% off our Black
[01:51:11] Friday bundle. And if you want the link,
[01:51:12] the link is in the description below.